Principles of regulating particle multiscale structures for controlling particle-cell interaction process

doi:10.1016/j.ces.2020.116343

	Principles of regulating particle multiscale structures for controlling particle-cell interaction process
	Song, Cui 1,2; Zhang, Xiao 1; Wei, Wei 1,2; Ma, Guanghui 1,2
刊名	CHEMICAL ENGINEERING SCIENCE
	2021-03-15
卷号	232 页码:19
关键词	Particles Multiscale structures Particle-cell interactions Biomedical applications
ISSN号	0009-2509
DOI	10.1016/j.ces.2020.116343
英文摘要	Particles make extensively physical contact with cells after entering the body, which mediate a series of particle-cell interaction processes. These interaction processes induce different physiological responses of cells and indicate the potential biomedical applications of particles. Hence, controlling the particlecell interaction processes have been attracting more and more attentions. Among factors that affect particle-cell interaction processes, regulating particle multiscale structures is the most dominant. To date, numerous principles have been developed, including integrating particles with different physicochemical properties such as size, shape, elasticity and surface chemistry by various preparation technologies, coating particle surface with cell membrane to endow its biomimetic properties, taking advantage of the particle's dimensional effect, etc. In this review, we will highlight recent progresses on these princi ples, and corresponding biomedical applications in drug delivery, immune modulation and tissue engineering. The challenges and perspectives of regulating particle multiscale structures for controlling interaction processes will also be discussed. (C) 2020 Elsevier Ltd. All rights reserved.
资助项目	Innovative Research Group Project of the National Natural Science Foundation of China[21821005] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDB29040303]
WOS关键词	RECEPTOR-MEDIATED ENDOCYTOSIS ; DRUG-DELIVERY SYSTEMS ; COATED GOLD NANOPARTICLES ; MESOPOROUS SILICA ; IMMUNE-RESPONSE ; GRAPHENE OXIDE ; IN-VITRO ; INTRACELLULAR TRAFFICKING ; TUMOR MICROENVIRONMENT ; MEMBRANE PENETRATION
WOS研究方向	Engineering
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000608126300009
资助机构	Innovative Research Group Project of the National Natural Science Foundation of China ; Strategic Priority Research Program of the Chinese Academy of Sciences
内容类型	期刊论文
源URL	[http://ir.ipe.ac.cn/handle/122111/43224]
专题	中国科学院过程工程研究所
通讯作者	Wei, Wei; Ma, Guanghui
作者单位	1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Song, Cui,Zhang, Xiao,Wei, Wei,et al. Principles of regulating particle multiscale structures for controlling particle-cell interaction process[J]. CHEMICAL ENGINEERING SCIENCE,2021,232:19.
APA	Song, Cui,Zhang, Xiao,Wei, Wei,&Ma, Guanghui.(2021).Principles of regulating particle multiscale structures for controlling particle-cell interaction process.CHEMICAL ENGINEERING SCIENCE,232,19.
MLA	Song, Cui,et al."Principles of regulating particle multiscale structures for controlling particle-cell interaction process".CHEMICAL ENGINEERING SCIENCE 232(2021):19.