Porphyrin/Ionic-Liquid Co-assembly Polymorphism Controlled by Liquid-Liquid Phase Separation

doi:10.1002/anie.202007459

	Porphyrin/Ionic-Liquid Co-assembly Polymorphism Controlled by Liquid-Liquid Phase Separation
	Yuan, Chengqian 2; Yang, Mengyao 2,3; Ren, Xiaokang 2,3; Zou, Qianli 2; Yan, Xuehai 1,2,3
刊名	ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
	2020-08-11
页码	6
关键词	co-assembly ionic liquids liquid-liquid phase separation nucleation porphyrin
ISSN号	1433-7851
DOI	10.1002/anie.202007459
英文摘要	Understanding and controlling multicomponent co-assembly is of primary importance in different fields, such as materials fabrication, pharmaceutical polymorphism, and supramolecular polymerization, but these aspects have been a long-standing challenge. Herein, we discover that liquid-liquid phase separation (LLPS) into ion-cluster-rich and ion-cluster-poor liquid phases is the first step prior to co-assembly nucleation based on a model system of water-soluble porphyrin and ionic liquids. The LLPS-formed droplets serve as the nucleation precursors, which determine the resulting structures and properties of co-assemblies. Co-assembly polymorphism and tunable supramolecular phase transition behaviors can be achieved by regulating the intermolecular interactions at the LLPS stage. These findings elucidate the key role of LLPS in multicomponent co-assembly evolution and enable it to be an effective strategy to control co-assembly polymorphism as well as supramolecular phase transitions.
资助项目	National Natural Science Foundation of China[21802143] ; National Natural Science Foundation of China[215223078] ; National Natural Science Foundation of China[21977095] ; National Natural Science Fund BRICS STI Framework Programme[51861145304] ; Key Research Program of Frontier Sciences of Chinese Academy of Sciences (CAS)[QYZDB-SSW-JSC034] ; National Natural Science Foundation of Hebei Province[2020103036]
WOS关键词	IONIC LIQUIDS ; PEPTIDE ; NUCLEATION
WOS研究方向	Chemistry
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000557829000001
资助机构	National Natural Science Foundation of China ; National Natural Science Fund BRICS STI Framework Programme ; Key Research Program of Frontier Sciences of Chinese Academy of Sciences (CAS) ; National Natural Science Foundation of Hebei Province
内容类型	期刊论文
源URL	[http://ir.ipe.ac.cn/handle/122111/41618]
专题	中国科学院过程工程研究所
通讯作者	Yan, Xuehai
作者单位	1.Chinese Acad Sci, Ctr Mesosci, Inst Proc Engn, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China 3.Univ Chinese Acad Sci, Sch Chem Engn, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Yuan, Chengqian,Yang, Mengyao,Ren, Xiaokang,et al. Porphyrin/Ionic-Liquid Co-assembly Polymorphism Controlled by Liquid-Liquid Phase Separation[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2020:6.
APA	Yuan, Chengqian,Yang, Mengyao,Ren, Xiaokang,Zou, Qianli,&Yan, Xuehai.(2020).Porphyrin/Ionic-Liquid Co-assembly Polymorphism Controlled by Liquid-Liquid Phase Separation.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,6.
MLA	Yuan, Chengqian,et al."Porphyrin/Ionic-Liquid Co-assembly Polymorphism Controlled by Liquid-Liquid Phase Separation".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020):6.