Efficacy of a Chitin-Based Water-Soluble Derivative in Inducing Purpureocillium lilacinum against Nematode Disease (Meloidogyne incognita)

doi:10.3390/ijms22136870

CORC > 海洋研究所 > 中国科学院海洋研究所 > 实验海洋生物学重点实验室

	Efficacy of a Chitin-Based Water-Soluble Derivative in Inducing Purpureocillium lilacinum against Nematode Disease (Meloidogyne incognita)
	Zhan, Jiang 1,2,3; Qin, Yukun 2,3; Gao, Kun 1,2,3; Fan, Zhaoqian 2,3; Wang, Linsong 2,3; Xing, Ronge 2,3; Liu, Song 2,3; Li, Pengcheng 2,3
刊名	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
	2021-07-01
卷号	22 期号:13 页码:19
关键词	biological control plant parasitic nematodes chitin Purpureocillium lilacinum 6-oxychitin
DOI	10.3390/ijms22136870
通讯作者	Qin, Yukun(ykqin@qdio.ac.cn) ; Li, Pengcheng(pcli@qdio.ac.cn)
英文摘要	Plant-parasitic nematodes cause severe economic losses annually which has been a persistent problem worldwide. As current nematicides are highly toxic, prone to drug resistance, and have poor stability, there is an urgent need to develop safe, efficient, and green strategies. Natural active polysaccharides such as chitin and chitosan with good biocompatibility and biodegradability and inducing plant disease resistance have attracted much attention, but their application is limited due to their poor solubility. Here, we prepared 6-oxychitin with good water solubility by introducing carboxylic acid groups based on retaining the original skeleton of chitin and evaluated its potential for nematode control. The results showed that 6-oxychitin is a better promoter of the nematicidal potential of Purpureocillium lilacinum than other water-soluble chitin derivatives. After treatment, the movement of J2s and egg hatching were obviously inhibited. Further plant experiments found that it can destroy the accumulation and invasion of nematodes, and has a growth-promoting effect. Therefore, 6-oxychitin has great application potential in the nematode control area.
资助项目	National Key R&D Program of China[2018YFC03113] ; National Key R&D Program of China[2019YFD0900705] ; National Natural Science Foundation of China[42076126] ; Shandong Provincial Natural Science Foundation[ZR2020MD072] ; Qingdao Applied Basic Research Project[19-6-2-34-cg] ; Qingdao science and technology demonstration and guidance project[20-3-422-nsh] ; Science and Technology Plan Project of Shinan District, Qingdao[2020-2-013-QT]
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
语种	英语
出版者	MDPI
WOS记录号	WOS:000671106400001
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/176990]
专题	海洋研究所_实验海洋生物学重点实验室
通讯作者	Qin, Yukun; Li, Pengcheng
作者单位	1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Pilot Natl Lab Marine Sci & Technol Qingdao, Lab Marine Drugs & Bioprod, 1 Wenhai Rd, Qingdao 266237, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, CAS & Shandong Prov Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Zhan, Jiang,Qin, Yukun,Gao, Kun,et al. Efficacy of a Chitin-Based Water-Soluble Derivative in Inducing Purpureocillium lilacinum against Nematode Disease (Meloidogyne incognita)[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2021,22(13):19.
APA	Zhan, Jiang.,Qin, Yukun.,Gao, Kun.,Fan, Zhaoqian.,Wang, Linsong.,...&Li, Pengcheng.(2021).Efficacy of a Chitin-Based Water-Soluble Derivative in Inducing Purpureocillium lilacinum against Nematode Disease (Meloidogyne incognita).INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,22(13),19.
MLA	Zhan, Jiang,et al."Efficacy of a Chitin-Based Water-Soluble Derivative in Inducing Purpureocillium lilacinum against Nematode Disease (Meloidogyne incognita)".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22.13(2021):19.