Cadinane and carotane derivatives from the marine algicolous fungus Trichoderma virens RR-dl-6-8

doi:10.1016/j.fitote.2020.104715

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室 > 海岸带生物学与生物资源利用所重点实验室

	Cadinane and carotane derivatives from the marine algicolous fungus Trichoderma virens RR-dl-6-8
	Song, Yin-Ping 1; Ji, Nai-Yun 1; Shi, Xiao-Shan 2; Wang, Bin-Gui 2
刊名	FITOTERAPIA
	2020-10
卷号	146 页码:104715
关键词	Trichoderma virens Sesquiterpene Cadinane Carotane
ISSN号	0367-326X
DOI	10.1016/j.fitote.2020.104715
英文摘要	Eight cadinane derivatives, trichocadinins H - N (1-7) and methylhydroheptelidate (8), and two carotane derivatives, 14-O-methyltrichocarotin G (9) and 14-O-methyl CAF-603 (10), including eight new ones (1-6, 9, and 10), were isolated from the culture of Trichoderma virens RR-dl-6-8 obtained from the organohalogen-enriched marine red alga Rhodomela confervoides. Their structures and relative configurations were established by analysis of NMR and mass spectroscopic data, and the absolute configurations were assigned on the basis of ECD curves, highlighted by the ECD diversity of carboxylic acid derivatives. Among the isolates, 1 with a halogen atom and 8, a new naturally occurring compound, are 2,3-seco-cadinane sesquiterpenes, and the epimeric 2 and 3 feature a 2-nor-cadinane skeleton. A commercially-sourced compound with the same planar structure as that of 7 has been reported in a patent, but its configuration was not given. Compounds 1-10 exhibited growth inhibition of some marine phytoplankton species.
WOS关键词	SECONDARY METABOLITES
WOS研究方向	Pharmacology & Pharmacy
语种	英语
WOS记录号	WOS:000580427700061
资助机构	Natural Science Foundation for Distinguished Young Scholars of Shandong Province [JQ201712] ; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31670355] ; Youth Innovation Promotion Association of the CAS [Y201734] ; Shuangbai Plan of Yantai [2018-3] ; Taishan Scholar Project Special Funding [tsqn201909164]
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/30494]
专题	烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
作者单位	1.Chinese Acad Sci, Ctr Ocean Megasci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; 2.Chinese Acad Sci, Ctr Ocean Megasci, Inst Oceanol,Key Lab Expt Marine Biol, Lab Marine Biol & Biotechnol,Qingdao Natl Lab Mar, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Song, Yin-Ping,Ji, Nai-Yun,Shi, Xiao-Shan,et al. Cadinane and carotane derivatives from the marine algicolous fungus Trichoderma virens RR-dl-6-8[J]. FITOTERAPIA,2020,146:104715.
APA	Song, Yin-Ping,Ji, Nai-Yun,Shi, Xiao-Shan,&Wang, Bin-Gui.(2020).Cadinane and carotane derivatives from the marine algicolous fungus Trichoderma virens RR-dl-6-8.FITOTERAPIA,146,104715.
MLA	Song, Yin-Ping,et al."Cadinane and carotane derivatives from the marine algicolous fungus Trichoderma virens RR-dl-6-8".FITOTERAPIA 146(2020):104715.