A TRIM insertion in the promoter of Ms2 causes male sterility in wheat

doi:10.1111/jipb.12553

CORC > 植物研究所 > 中国科学院植物研究所 > 系统与进化植物学国家重点实验室

	A TRIM insertion in the promoter of Ms2 causes male sterility in wheat
	Xia, Chuan ; Zhang, Lichao ; Zou, Cheng ; Gu, Yongqiang 2; Duan, Jialei ; Zhao, Guangyao ; Wu, Jiajie ; Liu, Yue ; Fang, Xiaohua 3; Gao, Lifeng
刊名	NATURE COMMUNICATIONS
	2017
卷号	8
ISSN号	2041-1723
DOI	10.1111/jipb.12553
文献子类	Article
英文摘要	The male-sterile ms2 mutant has been known for 40 years and has become extremely important in the commercial production of wheat. However, the gene responsible for this phenotype has remained unknown. Here we report the map-based cloning of the Ms2 gene. The Ms2 locus is remarkable in several ways that have implications in basic biology. Beyond having no functional annotation, barely detectable transcription in fertile wild-type wheat plants, and accumulated destructive mutations in Ms2 orthologs, the Ms2 allele in the ms2 mutant has acquired a terminal-repeat retrotransposon in miniature (TRIM) element in its promoter. This TRIM element is responsible for the anther-specific Ms2 activation that confers male sterility. The identification of Ms2 not only unravels the genetic basis of a historically important breeding trait, but also shows an example of how a TRIM element insertion near a gene can contribute to genetic novelty and phenotypic plasticity.
学科主题	Biochemistry & Molecular Biology ; Plant Sciences
出版地	LONDON
WOS关键词	TERMINAL-REPEAT RETROTRANSPOSONS ; POLLEN DEVELOPMENT ; MINIATURE TRIM ; DRAFT GENOME ; GENE ; PROTEIN ; RICE ; EVOLUTIONARY ; ARABIDOPSIS ; ANTHER
语种	英语
出版者	NATURE PUBLISHING GROUP
WOS记录号	WOS:000403018500001
资助机构	National Key Research and Development Program of China [2016YFD0100302, 2016YFD0101802] ; National Transgenic Research Project of China [2009ZX08009-110B] ; National Basic Research Program of ChinaNational Basic Research Program of China [2004CB117202, 2010CB125902] ; CAAS-Innovation Team Project
内容类型	期刊论文
源URL	[http://ir.ibcas.ac.cn/handle/2S10CLM1/22296]
专题	系统与进化植物学国家重点实验室
作者单位	1.Chinese Acad Sci, Inst Genet & Dev Biol, State Key Lab Mol Dev Biol, Beijing 100101, Peoples R China 2.Chinese Acad Agr Sci, Natl Key Facil Crop Gene Resources & Genet Improv, Key Lab Crop Gene Resources & Germplasm Enhanceme, Minist Agr,Inst Crop Sci, Beijing 100081, Peoples R China 3.ARS, USDA, Western Reg Res Ctr, Albany, CA 94710 USA 4.Chinese Acad Sci, Inst Bot, State Key Lab Systemat & Evolutionary Bot, Beijing 100093, Peoples R China
推荐引用方式 GB/T 7714	Xia, Chuan,Zhang, Lichao,Zou, Cheng,et al. A TRIM insertion in the promoter of Ms2 causes male sterility in wheat[J]. NATURE COMMUNICATIONS,2017,8.
APA	Xia, Chuan.,Zhang, Lichao.,Zou, Cheng.,Gu, Yongqiang.,Duan, Jialei.,...&Kong, Xiuying.(2017).A TRIM insertion in the promoter of Ms2 causes male sterility in wheat.NATURE COMMUNICATIONS,8.
MLA	Xia, Chuan,et al."A TRIM insertion in the promoter of Ms2 causes male sterility in wheat".NATURE COMMUNICATIONS 8(2017).