Evolution of Darwin's Peloric Gloxinia (Sinningia speciosa) Is Caused by a Null Mutation in a Pleiotropic TCP Gene

doi:10.1093/molbev/msy090

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	Evolution of Darwin's Peloric Gloxinia (Sinningia speciosa) Is Caused by a Null Mutation in a Pleiotropic TCP Gene
	Dong, Yang 3; Liu, Jing ; Li, Peng-Wei ; Li, Chao-Qun ; Lu, Tian-Feng ; Yang, Xia ; Wang, Yin-Zheng
刊名	MOLECULAR BIOLOGY AND EVOLUTION
	2018
卷号	35 期号:8 页码:1901-1915
关键词	peloric gloxinia Sinningia speciosa domestication molecular mechanism floral horizontal orientation pleiotropic gene
ISSN号	0737-4038
DOI	10.1093/molbev/msy090
文献子类	Article
英文摘要	Unlike most crops, which were domesticated through long periods of selection by ancient humans, horticultural plants were primarily domesticated through intentional selection over short time periods. The molecular mechanisms underlying the origin and spread of novel traits in the domestication process have remained largely unexplored in horticultural plants. Gloxinia (Sinningia speciosa), whose attractive peloric flowers influenced the thoughts of Darwin, have been cultivated since the early 19th century, but its origin and genetic basis are currently unknown. By employing multiple experimental approaches including genetic analysis, genotype-phenotype associations, gene expression analysis, and functional interrogations, we showed that a single gene encoding a TCP protein, SsCYC, controls both floral orientation and zygomorphy in gloxinia. We revealed that a causal mutation responsible for the development of peloric gloxinia lies in a 10-bp deletion in the coding sequence of SsCYC. By combining genetic inference and literature searches, we have traced the putative ancestor and reconstructed the domestication path of the peloric gloxinia, in which a 10-bp deletion in SsCYC under selection triggered its evolution from the wild progenitor. The results presented here suggest that a simple genetic change in a pleiotropic gene can promote the elaboration of floral organs under intensive selection pressure.
学科主题	Biochemistry & Molecular Biology ; Evolutionary Biology ; Genetics & Heredity
电子版国际标准刊号	1537-1719
出版地	OXFORD
WOS关键词	ADAPTIVE EVOLUTION ; AQUILEGIA-FORMOSA ; FLORAL SYMMETRY ; FLOWERS ; TRANSFORMATION ; GESNERIACEAE ; SOFTWARE ; TRAITS ; ORIGIN ; DOMESTICATION
语种	英语
出版者	OXFORD UNIV PRESS
WOS记录号	WOS:000441143000006
资助机构	National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31470333, 31530003, 31400205] ; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2014M550878, 2015T80151]
内容类型	期刊论文
源URL	[http://ir.ibcas.ac.cn/handle/2S10CLM1/20638]
专题	系统与进化植物学国家重点实验室
作者单位	1.Chinese Acad Sci, Inst Bot, State Key Lab Systemat & Evolutionary Bot, Beijing, Peoples R China 2.John Innes Ctr, Dept Crop Genet, Norwich Res Pk, Norwich, Norfolk, England 3.Univ Chinese Acad Sci, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Dong, Yang,Liu, Jing,Li, Peng-Wei,et al. Evolution of Darwin's Peloric Gloxinia (Sinningia speciosa) Is Caused by a Null Mutation in a Pleiotropic TCP Gene[J]. MOLECULAR BIOLOGY AND EVOLUTION,2018,35(8):1901-1915.
APA	Dong, Yang.,Liu, Jing.,Li, Peng-Wei.,Li, Chao-Qun.,Lu, Tian-Feng.,...&Wang, Yin-Zheng.(2018).Evolution of Darwin's Peloric Gloxinia (Sinningia speciosa) Is Caused by a Null Mutation in a Pleiotropic TCP Gene.MOLECULAR BIOLOGY AND EVOLUTION,35(8),1901-1915.
MLA	Dong, Yang,et al."Evolution of Darwin's Peloric Gloxinia (Sinningia speciosa) Is Caused by a Null Mutation in a Pleiotropic TCP Gene".MOLECULAR BIOLOGY AND EVOLUTION 35.8(2018):1901-1915.