Impact of scandium on mechanical properties, corrosion behavior, friction and wear performance, and cytotoxicity of a beta-type Ti-24Nb-38Zr-2Mo alloy for orthopedic applications

doi:10.1016/j.actbio.2021.07.061

	Impact of scandium on mechanical properties, corrosion behavior, friction and wear performance, and cytotoxicity of a beta-type Ti-24Nb-38Zr-2Mo alloy for orthopedic applications
	Tong, Xian 2,3; Sun, Quanxiang 2; Zhang, Dechuang 2; Wang, Kun 4; Dai, Yilong 2; Shi, Zimu 5; Li, Yuncang 1; Dargusch, Matthew 6; Huang, Shengbin 3; Ma, Jianfeng 3
刊名	ACTA BIOMATERIALIA
	2021-10-15
卷号	134
关键词	Corrosion properties Cytocompatibility Friction and wear resistance Mechanical properties Scandium Ti-Nb-Zr-Mo alloy
ISSN号	1742-7061
DOI	10.1016/j.actbio.2021.07.061
通讯作者	Zhang, Dechuang(dczhang@xtu.edu.cn) ; Shi, Zimu(shizimu@issp.ac.cn) ; Wen, Cuie(cuie.wen@rmit.edu.au) ; Lin, Jixing(jixing.lin@wmu.edu.cn)
英文摘要	beta-type titanium (Ti) alloys have been extensively investigated as orthopedic implant materials due to their unique combination of low elastic modulus, high specific strength, corrosion resistance, and biocompatibility. In this study the mechanical properties, corrosion behavior, friction and wear performance, and cytotoxicity of beta-type Ti-24Nb-38Zr-2Mo (TNZM) and Ti-24Nb-38Zr-2Mo-0.1Sc (TNZMS) have been comparatively investigated for orthopedic applications. Cold-rolling (CR) and cold-rolling plus solution treatment (CR + ST) were performed on the as-cast (AC) alloys and their microstructures and material properties were characterized. The impact of Sc addition on the mechanical and corrosion properties, friction and wear behavior, and in vitro cytocompatibility of the TNZMS alloy was assessed. The CR + ST TNZMS alloy exhibited the best combination of properties among all the alloy samples, with a yield strength of 780 MPa, ultimate strength of 809 MPa, elongation of 19%, Young's modulus of 65.4 GPa, and hardness of 265 HV. Electrochemical testing in Hanks' Solution indicated that the CR + ST TNZMS sample also showed the highest corrosion resistance with a corrosion potential of-0.234 V, corrosion current density of 0.07 mu A/cm2, and corrosion rate of 1.2 mu m/y. Friction and wear testing revealed that the TNZMS alloy showed higher wear resistance compared to the TNZM alloy and the wear resistance of the different sam ples was ranked CR > CR + ST > AC. Finally, both the CR + ST TNZM and TNZMS showed no-cytotoxicity towards MG-63 cells and the TNZMS exhibited slightly higher cytocompatibility than the TNZM alloy. Statement of significance This work reports the beta-type Ti-24Nb-38Zr-2Mo (TNZM) and Ti-24Nb-38Zr-2Mo-0.1Sc (TNZMS) alloys fabricated by as-cast (AC), cold-rolling (CR), and cold-rolling plus solution-treatment (CR + ST) for potential orthopedic applications. The experimental results showed that the TNZMS alloy exhibited significantly enhanced mechanical, wear, and corrosion properties than those of TNZM alloy; and the CR + ST TNZMS possess a unique combination of the best mechanical and corrosion properties including a yield strength of 780 MPa, ultimate strength of 809 MPa, elongation of 19%, Young's modulus of 65.4 GPa, and corrosion rate of 1.2 mu m/y in Hanks' Solution. Both the CR + ST TNZM and TNZMS alloys exhibited non-cytotoxicity towards MG-63 cells and TNZMS showed a higher cytocompatibility than that of TNZM. (c) 2021 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
WOS关键词	TITANIUM-ALLOYS ; DISLOCATION DENSITY ; PURE TITANIUM ; SHAPE-MEMORY ; TA ALLOYS ; RESISTANCE ; MICROSTRUCTURE ; STRENGTH ; ZR ; IMPLANT
WOS研究方向	Engineering ; Materials Science
语种	英语
出版者	ELSEVIER SCI LTD
WOS记录号	WOS:000710049000004
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/125783]
专题	中国科学院合肥物质科学研究院
通讯作者	Zhang, Dechuang; Shi, Zimu; Wen, Cuie; Lin, Jixing
作者单位	1.RMIT Univ, Sch Engn, Melbourne, Vic 3001, Australia 2.Xiangtan Univ, Sch Mat Sci & Engn, Xiangtan 411105, Peoples R China 3.Wenzhou Med Univ, Sch & Hosp Stomatol, Inst Stomatol, Wenzhou 325027, Peoples R China 4.Zhejiang Ind & Trade Vocat Coll, Dept Mat Engn, Wenzhou 325003, Peoples R China 5.Chinese Acad Sci, Inst Solid State Phys, Key Lab Mat Phys, Hefei 230031, Peoples R China 6.Univ Queensland, Ctr Adv Mat Proc & Mfg AMPAM, Brisbane, Qld 4072, Australia
推荐引用方式 GB/T 7714	Tong, Xian,Sun, Quanxiang,Zhang, Dechuang,et al. Impact of scandium on mechanical properties, corrosion behavior, friction and wear performance, and cytotoxicity of a beta-type Ti-24Nb-38Zr-2Mo alloy for orthopedic applications[J]. ACTA BIOMATERIALIA,2021,134.
APA	Tong, Xian.,Sun, Quanxiang.,Zhang, Dechuang.,Wang, Kun.,Dai, Yilong.,...&Lin, Jixing.(2021).Impact of scandium on mechanical properties, corrosion behavior, friction and wear performance, and cytotoxicity of a beta-type Ti-24Nb-38Zr-2Mo alloy for orthopedic applications.ACTA BIOMATERIALIA,134.
MLA	Tong, Xian,et al."Impact of scandium on mechanical properties, corrosion behavior, friction and wear performance, and cytotoxicity of a beta-type Ti-24Nb-38Zr-2Mo alloy for orthopedic applications".ACTA BIOMATERIALIA 134(2021).