Copper-Catalyzed Huisgen and Oxidative Huisgen Coupling Reactions Controlled by Polysiloxane-Supported Amines (AFPs) for the Divergent Synthesis of Triazoles and Bistriazoles

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	Copper-Catalyzed Huisgen and Oxidative Huisgen Coupling Reactions Controlled by Polysiloxane-Supported Amines (AFPs) for the Divergent Synthesis of Triazoles and Bistriazoles
	Zheng ZJ(郑战江)1; Ye F(叶飞)1; Zheng LS(郑龙生)1; Yang KF(杨科芳)1; Lai GQ(来国桥)1; Xu LW(徐利文)1,2
刊名	Chemistry - A European Journal
	2012
卷号	18 期号:44 页码:14094-14099
关键词	bistriazoles click chemistry copper oxidative coupling polysiloxanes
ISSN号	0947-6539
通讯作者	徐利文
英文摘要	An interesting example of a divergent catalysis with a copper(I) and amine-functional macromolecular polysiloxanes system was successfully presented in click chemistry. In this manuscript, we demonstrate the remarkable ability of the secondary amine-functional polysiloxane to induce oxidative coupling in the copper-mediated Huisgen reactions of azides and alkynes, thereby achieving good yields and selectivities. The click reactions mediated by a polysiloxane-supported secondary amine allow the preparation of novel heterocyclic compounds, that is, bistriazoles. Comparably, it is also surprising that the use of a diamine-functional polysiloxane as ligand led to a classic Huisgen [3+2] cycloaddition in excellent yields. From the results of the present amine-functional polysiloxanes-controlled Huisgen reaction or oxidative Huisgen coupling reaction to divergent products and the proposed mechanism, we suggested that the mononuclear bistriazole-copper complex stabilized and dispersed by the secondary amine-functional polysiloxane was beneficial to prevalent the way to oxidative coupling.
学科主题	物理化学
收录类别	SCI
资助信息	the National Natural Science Founder of China (No. 20973051;21173064);the Zhejiang Provincial Natural Science Foundation of China (Q12B020037);the Qianjiang talent project of Zhejiang Province of China (No. 2010R0017);the Program for Excellent Young Teachers in Hangzhou Normal University (HNUEYT, JTAS 2011-01-014)
语种	英语
WOS记录号	WOS:000310473900026
公开日期	2013-10-11
内容类型	期刊论文
源URL	[http://210.77.64.217/handle/362003/3821]
专题	兰州化学物理研究所_OSSO国家重点实验室
作者单位	1.Hangzhou Normal Univ, Key Lab Organosilicon Chem & Mat Technol, Minist Educ, Hangzhou 310012, Zhejiang, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China
推荐引用方式 GB/T 7714	Zheng ZJ,Ye F,Zheng LS,et al. Copper-Catalyzed Huisgen and Oxidative Huisgen Coupling Reactions Controlled by Polysiloxane-Supported Amines (AFPs) for the Divergent Synthesis of Triazoles and Bistriazoles[J]. Chemistry - A European Journal,2012,18(44):14094-14099.
APA	Zheng ZJ,Ye F,Zheng LS,Yang KF,Lai GQ,&Xu LW.(2012).Copper-Catalyzed Huisgen and Oxidative Huisgen Coupling Reactions Controlled by Polysiloxane-Supported Amines (AFPs) for the Divergent Synthesis of Triazoles and Bistriazoles.Chemistry - A European Journal,18(44),14094-14099.
MLA	Zheng ZJ,et al."Copper-Catalyzed Huisgen and Oxidative Huisgen Coupling Reactions Controlled by Polysiloxane-Supported Amines (AFPs) for the Divergent Synthesis of Triazoles and Bistriazoles".Chemistry - A European Journal 18.44(2012):14094-14099.