Genome of the butterfly hillstream loach provides insights into adaptations to torrential mountain stream life

doi:10.1111/1755-0998.13400

CORC > 深海科学与工程研究所 > 中国科学院深海科学与工程研究所 > 深海科学研究部 > 深海生物学研究室 > 深海鱼类物种与基因组多样性的研究

	Genome of the butterfly hillstream loach provides insights into adaptations to torrential mountain stream life
	Deng, Yu 2,3; Meng, Minghui 2; Fang, Jian 2; Jiang, Haifeng 2,3; Sun, Ning 2,3; Lv, Wenqi 2,3; Lei, Yi 2,3; Wang, Cheng 2,3; Bo, Jing 3,4; Liu, Chun 5
刊名	MOLECULAR ECOLOGY RESOURCES
	2021-05-12
页码	14
关键词	adaptation butterfly hillstream loach craniofacial skeletogenesis unculi
ISSN号	1755-098X
DOI	10.1111/1755-0998.13400
英文摘要	Butterfly hillstream loach (Beaufortia kweichowensis), a benthic fish in the torrential mountain streams, possesses a totally flat ventrum, flattened craniofacial and body skeletons, and enlarged paired fins covered by substantially small keratinous structures. However, little is known about the genetic basis of these specialized morphological adaptations. Here we present a 448.52-Mb genome assembly with contig N50 length of 5.53 Mb by integrating Illumina short-read sequencing, Nanopore long-read sequencing and HiC-based chromatin map. Demographic history reconstruction of the butterfly hillstream loach reveals that the population dynamics is correlated with the different stages of uplifting of the Tibetan Plateau. Comparative genomic analysis finds evidence of six keratin genes in butterfly hillstream loach evolving under positive selection. Within these genes, two keratin genes exhibit species-specific and divergent amino acid changes, suggesting a role in the formation of the unculi. Additionally, a series of positively selected genes, rapid evolving genes, specific variant genes and expanded gene families are found, including genes related to Hedgehog, Notch and BMP pathways, which may be involved in craniofacial development. These findings may have important implications for understanding the genetic basis of phenotypic adaptation to torrential mountain stream life.
资助项目	National Natural Science Foundation of China[31702016] ; National Natural Science Foundation of China[31972866] ; Strategic Priority Research Program of Chinese Academy of Sciences[XDB31040104] ; Youth Innovation Promotion Association ; Chinese Academy of Sciences
WOS关键词	PHYLOGENETIC ANALYSIS ; GENE FAMILY ; EVOLUTION ; SEQUENCE ; HEDGEHOG ; ALIGNMENT ; BALITORIDAE ; PROGRAM ; CYPRINIFORMES ; DIVERGENCE
WOS研究方向	Biochemistry & Molecular Biology ; Environmental Sciences & Ecology ; Evolutionary Biology
语种	英语
出版者	WILEY
WOS记录号	WOS:000649249600001
资助机构	National Natural Science Foundation of China ; Strategic Priority Research Program of Chinese Academy of Sciences ; Youth Innovation Promotion Association ; Chinese Academy of Sciences
内容类型	期刊论文
源URL	[http://ir.idsse.ac.cn/handle/183446/8630]
专题	深海科学研究部_深海生物学研究室_深海鱼类物种与基因组多样性的研究
通讯作者	Wang, Ying; Yang, Liandong; He, Shunping
作者单位	1.Jianghan Univ, Coll Life Sci, Hubei Engn Res Ctr Protect & Utilizat Special Bio, Wuhan, Peoples R China 2.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China 4.Chinese Acad Sci, Inst Deep Sea Sci & Engn, Sanya, Peoples R China 5.BGI Shenzhen, BGI Genom, Shenzhen, Peoples R China 6.Chinese Acad Sci, Ctr Excellence Anim Evolut & Genet, Kunming, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Deng, Yu,Meng, Minghui,Fang, Jian,et al. Genome of the butterfly hillstream loach provides insights into adaptations to torrential mountain stream life[J]. MOLECULAR ECOLOGY RESOURCES,2021:14.
APA	Deng, Yu.,Meng, Minghui.,Fang, Jian.,Jiang, Haifeng.,Sun, Ning.,...&He, Shunping.(2021).Genome of the butterfly hillstream loach provides insights into adaptations to torrential mountain stream life.MOLECULAR ECOLOGY RESOURCES,14.
MLA	Deng, Yu,et al."Genome of the butterfly hillstream loach provides insights into adaptations to torrential mountain stream life".MOLECULAR ECOLOGY RESOURCES (2021):14.