Tracing the genetic footprints of vertebrate landing in non-teleost ray-finned fishes

doi:10.1016/j.cell.2021.01.046

CORC > 深海科学与工程研究所 > 中国科学院深海科学与工程研究所 > 深海科学研究部 > 深海生物学研究室 > 深海鱼类物种与基因组多样性的研究

	Tracing the genetic footprints of vertebrate landing in non-teleost ray-finned fishes
	Bi, Xupeng 13,14; Wang, Kun 12; Yang, Liandong 14; Pan, Hailin 13; Jiang, Haifeng 14; Wei, Qiwei 11; Fang, Miaoquan 13; Yu, Hao 13; Zhu, Chenglong 12; Cai, Yiran 13
刊名	CELL
	2021-03-04
卷号	184 期号:5 页码:1377-+
ISSN号	0092-8674
DOI	10.1016/j.cell.2021.01.046
英文摘要	Rich fossil evidence suggests that many traits and functions related to terrestrial evolution were present long before the ancestor of lobe- and ray-finned fishes. Here, we present genome sequences of the bichir, paddlefish, bowfin, and alligator gar, covering all major early divergent lineages of ray-finned fishes. Our analyses show that these species exhibit many mosaic genomic features of lobe- and ray-finned fishes. In particular, many regulatory elements for limb development are present in these fishes, supporting the hypothesis that the relevant ancestral regulation networks emerged before the origin of tetrapods. Transcriptome analyses confirm the homology between the lung and swim bladder and reveal the presence of functional lung-related genes in early ray-finned fishes. Furthermore, we functionally validate the essential role of a jawed vertebrate highly conserved element for cardiovascular development. Our results imply the ancestors of jawed vertebrates already had the potential gene networks for cardio-respiratory systems supporting air breathing.
资助项目	Fish10K project ; Wuhan Frasergen Bioinformatics Co., Ltd. ; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences ; National Natural Science Foundation of China[41876179] ; National Natural Science Foundation of China[31972866] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDB13000000] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDB31020000] ; Villum Investigator grant from The Villum Foundation[25900] ; Guangdong Provincial Academician Workstation of BGI Synthetic Genomics[2017B090904014] ; Youth Innovation Promotion Association, Chinese Academy of Sciences
WOS研究方向	Biochemistry & Molecular Biology ; Cell Biology
语种	英语
出版者	CELL PRESS
WOS记录号	WOS:000629635700022
资助机构	Fish10K project ; Wuhan Frasergen Bioinformatics Co., Ltd. ; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences ; National Natural Science Foundation of China ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Villum Investigator grant from The Villum Foundation ; Guangdong Provincial Academician Workstation of BGI Synthetic Genomics ; Youth Innovation Promotion Association, Chinese Academy of Sciences
内容类型	期刊论文
源URL	[http://ir.idsse.ac.cn/handle/183446/8555]
专题	深海科学研究部_深海生物学研究室_深海鱼类物种与基因组多样性的研究
通讯作者	Wang, Wen; Zhu, Min; He, Shunping; Zhang, Guojie
作者单位	1.Chinese Acad Sci, Kunming Inst Zool, State Key Lab Genet Resources & Evolut, Kunming 650223, Yunnan, Peoples R China 2.Chinese Acad Sci, Ctr Excellence Anim Evolut & Genet, 32 Jiaochang Donglu, Kunming 650223, Yunnan, Peoples R China 3.BGI Shenzhen, Guangdong Prov Academician Workstn BGI Synthet Ge, Shenzhen 518120, Peoples R China 4.James D Watson Inst Genome Sci, Hangzhou, Peoples R China 5.Chinese Acad Sci, Tianjin Inst Ind Biotechnol, Tianjin, Peoples R China 6.CAS Ctr Excellence Life & Paleoenvironm, Beijing 100044, Peoples R China 7.Chinese Acad Sci, Inst Vertebrate Paleontol & Paleoanthropol, Key Lab Vertebrate Evolut & Human Origins, 142 Xi Zhi Men Wai St, Beijing 100044, Peoples R China 8.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 9.Chinese Acad Sci, Inst Zool, State Key Lab Integrated Management Pest Insects, Beijing 100101, Peoples R China 10.Chinese Acad Sci, Inst Zool, Key Lab Zool Systemat & Evolut, Beijing 100101, Peoples R China
推荐引用方式 GB/T 7714	Bi, Xupeng,Wang, Kun,Yang, Liandong,et al. Tracing the genetic footprints of vertebrate landing in non-teleost ray-finned fishes[J]. CELL,2021,184(5):1377-+.
APA	Bi, Xupeng.,Wang, Kun.,Yang, Liandong.,Pan, Hailin.,Jiang, Haifeng.,...&Zhang, Guojie.(2021).Tracing the genetic footprints of vertebrate landing in non-teleost ray-finned fishes.CELL,184(5),1377-+.
MLA	Bi, Xupeng,et al."Tracing the genetic footprints of vertebrate landing in non-teleost ray-finned fishes".CELL 184.5(2021):1377-+.