Sesquiterpenes from Artemisia Sieversiana and their anti-inflammatory activities

doi:10.1016/j.fitote.2021.104996

	Sesquiterpenes from Artemisia Sieversiana and their anti-inflammatory activities
	Nuermaimaiti, Muaitaer 1,2; Turak, Ablajan 2; Yang, Qing 3,4; Tang, Bixi 3,5; Zang, Yi 3,6; Li, Jia 3,6,7; Aisa, Haji Akber 2
刊名	FITOTERAPIA
	2021-10-01
卷号	154 页码:7
关键词	Artemisia sieversiana Dimeric guaianolides Sesquiterpenes Anti-inflammatory
ISSN号	0367-326X
DOI	10.1016/j.fitote.2021.104996
通讯作者	Aisa, Haji Akber(haji@ms.xjb.ac.cn)
英文摘要	Eight undescribed sesquiterpenes, including three dimeric guaianolides and five sesquiterpens, together with ten known ones, were isolated from the aerial parts of Artemisia sieversiana. Their structures were elucidated by extensive spectroscopic techniques and ECD calculation. The isolated compounds were tested for their anti-inflammatory effects against IL-1 beta, IL-6 and TNF-alpha in LPS-induced RAW 264.7 cells. Compounds 4, 9, 12, 15, 16 and 17 showed potent anti-inflammatory activities.
资助项目	Xinjiang International Science & Technology Cooperation Program[2019E01017] ; National Natural Science Foundation of China[U1703235] ; National Natural Science Foundation of China[31900291] ; Youth Innovation Promotion Association CAS
WOS关键词	DIMERIC GUAIANOLIDES ; DERIVATIVES ; LACTONES
WOS研究方向	Pharmacology & Pharmacy
语种	英语
出版者	ELSEVIER
WOS记录号	WOS:000703820600003
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/297478]
专题	中国科学院上海药物研究所
通讯作者	Aisa, Haji Akber
作者单位	1.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Basis Xinjiang Indigenous Med Plant, Urumqi 830011, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 4.Nanchang Univ, Sch Pharm, Dept Pharmacol, Nanchang 330006, Jiangxi, Peoples R China 5.Fudan Univ, Sch Pharm, China Dept Pharmacol, Shanghai 201203, Peoples R China 6.UCAS, Hangzhou Inst Adv Study, Sch Pharmaceut Sci & Technol, Hangzhou 310024, Peoples R China 7.Pilot Natl Lab Marine Sci & Technol Qingdao, Open Studio Druggabil Res Marine Nat Prod, 1 Wenhai Rd, Qingdao 266237, Peoples R China
推荐引用方式 GB/T 7714	Nuermaimaiti, Muaitaer,Turak, Ablajan,Yang, Qing,et al. Sesquiterpenes from Artemisia Sieversiana and their anti-inflammatory activities[J]. FITOTERAPIA,2021,154:7.
APA	Nuermaimaiti, Muaitaer.,Turak, Ablajan.,Yang, Qing.,Tang, Bixi.,Zang, Yi.,...&Aisa, Haji Akber.(2021).Sesquiterpenes from Artemisia Sieversiana and their anti-inflammatory activities.FITOTERAPIA,154,7.
MLA	Nuermaimaiti, Muaitaer,et al."Sesquiterpenes from Artemisia Sieversiana and their anti-inflammatory activities".FITOTERAPIA 154(2021):7.