Environmentally relevant concentrations of bifenthrin induce changes in behaviour, biomarkers, histological characteristics, and the transcriptome in Corbicula fluminea

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 中国科学院饮用水科学与技术重点实验室

	Environmentally relevant concentrations of bifenthrin induce changes in behaviour, biomarkers, histological characteristics, and the transcriptome in Corbicula fluminea
	Zhang, Huan; Hong, Xiangsheng; Yan, Saihong; Zha, Jinmiao; Qin, Jianhui
刊名	SCIENCE OF THE TOTAL ENVIRONMENT
	2020-08-01
卷号	728 页码:1-13
关键词	Pyrethroid Transcriptome Biomarkers Histopathology Behaviour
ISSN号	0048-9697
英文摘要	Bifenthrin (BF) is an insecticide that is commonly used to control agricultural and domestic pests and is widespread in aquatic environments. Although previous studies have found that BF is toxic to aquatic organisms, such a comprehensive study of the mechanism of toxic effects in bivalves is not common. In this study, to assess the toxic effects of BF on bivalves, adult Corbicula fluminea (C. fluminea) were exposed to 0, 1, 5, and 25 mu g/L BF for 15 days. Transcriptome analysis revealed that BF exposure significantly altered the expression of genes involved in detoxification, antioxidation, and metabolism. Moreover, the ROS content and GST activity at 25 mu g/L treatments were significantly increased (p < 0.05), and significant increases of MDA concentration and CAT activity were observed at 5 and 25 mu g/L treatments (p < 0.05). However, AChE activity was markedly inhibited at 25 mu g/L treatments (p < 0.05). In addition, vacuolation in the digestive tubules and the hemolytic infiltration of connective tissue were observed at all treatments, and the degeneration of the digestive tubule was observed at 5 and 25 mu g/L treatments. In the behavioural assay, the siphoning behaviour of C. fluminea was significantly inhibited at 25 mu g/L treatments (p < 0.05), whereas no significant change in burrowing behaviour was observed. Our findings suggested that BF exposure caused changes in detoxification, antioxidation, and metabolism pathways, biomarker activity or concentrations and histopathological characteristics, resulting in changes in behaviour. Therefore, our findings provide a basis for further evaluation of the toxicity of pyrethroid insecticides in bivalves.
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/45293]
专题	生态环境研究中心_中国科学院饮用水科学与技术重点实验室
推荐引用方式 GB/T 7714	Zhang, Huan,Hong, Xiangsheng,Yan, Saihong,et al. Environmentally relevant concentrations of bifenthrin induce changes in behaviour, biomarkers, histological characteristics, and the transcriptome in Corbicula fluminea[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2020,728:1-13.
APA	Zhang, Huan,Hong, Xiangsheng,Yan, Saihong,Zha, Jinmiao,&Qin, Jianhui.(2020).Environmentally relevant concentrations of bifenthrin induce changes in behaviour, biomarkers, histological characteristics, and the transcriptome in Corbicula fluminea.SCIENCE OF THE TOTAL ENVIRONMENT,728,1-13.
MLA	Zhang, Huan,et al."Environmentally relevant concentrations of bifenthrin induce changes in behaviour, biomarkers, histological characteristics, and the transcriptome in Corbicula fluminea".SCIENCE OF THE TOTAL ENVIRONMENT 728(2020):1-13.