Air pollution could drive global dissemination of antibiotic resistance genes

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 中国科学院饮用水科学与技术重点实验室

	Air pollution could drive global dissemination of antibiotic resistance genes
	Zhu, Guibing; Wang, Xiaomin; Yang, Ting; Su, Jianqiang; Qin, Yu; Wang, Shanyun; Gillings, Michael; Wang, Cheng; Ju, Feng; Lan, Bangrui
刊名	ISME JOURNAL
	2020-01
卷号	15 期号:1 页码:270-281
ISSN号	1751-7362
英文摘要	Antibiotic-resistant pathogens pose a significant threat to human health. Several dispersal mechanisms have been described, but transport of both microbes and antibiotic resistance genes (ARGs) via atmospheric particles has received little attention as a pathway for global dissemination. These atmospheric particles can return to the Earth's surface via rain or snowfall, and thus promote long-distance spread of ARGs. However, the diversity and abundance of ARGs in fresh snow has not been studied and their potential correlation with particulate air pollution is not well explored. Here, we characterized ARGs in 44 samples of fresh snow from major cities in China, three in North America, and one in Europe, spanning a gradient from pristine to heavily anthropogenically influenced ecosystems. High-throughput qPCR analysis of ARGs and mobile genetic elements (MGEs) provided strong indications that dissemination of ARGs in fresh snow could be exacerbated by air pollution, severely increasing the health risks of both air pollution and ARGs. We showed that snowfall did effectively spread ARGs from point sources over the Earth surface. Together our findings urge for better pollution control to reduce the risk of global dissemination of antibiotic resistance genes.
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/45236]
专题	生态环境研究中心_中国科学院饮用水科学与技术重点实验室
推荐引用方式 GB/T 7714	Zhu, Guibing,Wang, Xiaomin,Yang, Ting,et al. Air pollution could drive global dissemination of antibiotic resistance genes[J]. ISME JOURNAL,2020,15(1):270-281.
APA	Zhu, Guibing.,Wang, Xiaomin.,Yang, Ting.,Su, Jianqiang.,Qin, Yu.,...&Zhu, Yong-Guan.(2020).Air pollution could drive global dissemination of antibiotic resistance genes.ISME JOURNAL,15(1),270-281.
MLA	Zhu, Guibing,et al."Air pollution could drive global dissemination of antibiotic resistance genes".ISME JOURNAL 15.1(2020):270-281.