Understanding the Multiple Effects of PCBs on Lipid Metabolism

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 环境化学与生态毒理学国家重点实验室

	Understanding the Multiple Effects of PCBs on Lipid Metabolism
	Shan, Qiuli; Li, Hongmei; Chen, Ningning; Qu, Fan; Guo, Jing
刊名	DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY
	2020-01
卷号	13 页码:3691-3702
关键词	PCBs metabolism-disrupting chemicals hepatocytes lipid metabolism
ISSN号	1178-7007
英文摘要	Polychlorinated biphenyls (PCBs) are a typical class of environmental contaminants recently shown to be metabolism-disrupting chemicals. Lipids are a highly complex group of biomolecules that not only form the structural basis of biofilms but also act as signaling molecules and energy sources. Lipid metabolic disorders contribute to multiple diseases, including obesity, diabetes, fatty liver, and metabolic syndromes. Although previous literature has reported that PCBs can affect lipid metabolism, including lipid synthesis, uptake, and elimination, few systematic summaries of the detailed process of lipid metabolism caused by PCB exposure have been published. Lipid metabolic processes involve many molecules; however, the key factors that are sensitive to PCB exposure have not been fully clarified. Here, we summarize the recent developments in PCB research with a focus on biomarkers of lipid metabolic disorders related to environmental exposures.
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/44848]
专题	生态环境研究中心_环境化学与生态毒理学国家重点实验室
推荐引用方式 GB/T 7714	Shan, Qiuli,Li, Hongmei,Chen, Ningning,et al. Understanding the Multiple Effects of PCBs on Lipid Metabolism[J]. DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY,2020,13:3691-3702.
APA	Shan, Qiuli,Li, Hongmei,Chen, Ningning,Qu, Fan,&Guo, Jing.(2020).Understanding the Multiple Effects of PCBs on Lipid Metabolism.DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY,13,3691-3702.
MLA	Shan, Qiuli,et al."Understanding the Multiple Effects of PCBs on Lipid Metabolism".DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY 13(2020):3691-3702.