Self-assembly of pentapeptides in ethanol to develop organogels

doi:10.1039/d0sm01303j

CORC > 上海应用物理研究所 > 中国科学院上海应用物理研究所 > 中科院上海应用物理研究所2011-2017年

	Self-assembly of pentapeptides in ethanol to develop organogels
	Tan, TY ; Shen, ZW ; Wang, YJ ; Guo, Z ; Hu, J ; Zhang, Y
刊名	SOFT MATTER
	2020
卷号	16 期号:46 页码:10567-10573
关键词	TRANSCATHETER ARTERIAL EMBOLIZATION PERCUTANEOUS ALCOHOL INJECTION HEPATOCELLULAR-CARCINOMA ABLATION THERAPY GEL TRANSFORMATION RESECTION
ISSN号	1744-683X
DOI	10.1039/d0sm01303j
文献子类	期刊论文
英文摘要	Organogels have a wide variety of applications in the fields of chemistry, electricity, biomedicine and environmental engineering, which call for robust strategies for designing and developing novel organogelators. Here, we reported a pentapeptide, ECAYF, which was capable of forming a self-healing ethanol gel exhibiting viscoelastic and solid-like properties. The ethanol gel of ECAYF was stable for at least several months, suggesting strong non-covalent interactions between ethanol and the peptide in the gel. In the ethanol gel, self-assembled peptide fibrils were found to immobilize the ethanol molecules for gelation. Results also suggested that the EAF-5 peptide adopted H-bonding beta-sheet secondary structures, which further assembled into fibrils. Meanwhile, the self-assembly of the ECAYF peptide in mixtures of differently fractioned ethanol and H2O was observed, which clearly indicated that ethanol promoted the assembly of ECAYF in the solutions. These findings are helpful in understanding the roles of organic solvents as well as the complicated interactions between the solvent and gelator molecules in gelation.
语种	英语
内容类型	期刊论文
源URL	[http://ir.sinap.ac.cn/handle/331007/33128]
专题	上海应用物理研究所_中科院上海应用物理研究所2011-2017年
作者单位	1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Shanghai Adv Res Inst, Zhangjiang Lab, Shanghai 201210, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Appl Phys, Key Lab Interfacial Phys & Technol, Shanghai 201800, Peoples R China
推荐引用方式 GB/T 7714	Tan, TY,Shen, ZW,Wang, YJ,et al. Self-assembly of pentapeptides in ethanol to develop organogels[J]. SOFT MATTER,2020,16(46):10567-10573.
APA	Tan, TY,Shen, ZW,Wang, YJ,Guo, Z,Hu, J,&Zhang, Y.(2020).Self-assembly of pentapeptides in ethanol to develop organogels.SOFT MATTER,16(46),10567-10573.
MLA	Tan, TY,et al."Self-assembly of pentapeptides in ethanol to develop organogels".SOFT MATTER 16.46(2020):10567-10573.