Age-related alterations of default mode network in autobiographical memory: Recent versus remote events

doi:10.1016/j.nlm.2020.107341

CORC > 心理研究所 > 中国科学院心理研究所 > 中国科学院心理健康重点实验室

	Age-related alterations of default mode network in autobiographical memory: Recent versus remote events
	Xu, Hong-Zhou 2; Xu, Xiao-Xiao 2; Lei, Xu 2; Yu, Jing 1,2
刊名	NEUROBIOLOGY OF LEARNING AND MEMORY
	2021
卷号	177 页码:8
关键词	Aging Autobiographical memory Default mode network Temporal distance Functional connectivity
ISSN号	1074-7427
DOI	10.1016/j.nlm.2020.107341
通讯作者	Yu, Jing(helen12@swu.edu.cn)
英文摘要	Previous studies have shown that the vividness of autobiographical memory decreases over time, and older adults often retrieve fewer details than young adults. However, the age-by-temporal distance (i.e., recent versus remote events) effect on autobiographical memory and underlying neural mechanisms are less understood. We recruited 25 young adults and 27 older adults to perform an fMRI-adapted autobiographical memory task with different temporal distances. The results showed that older adults' vividness ratings were generally higher than that of young adults, but were less sensitive to temporal distances. For neural imaging, an age-by-temporal distance effect was found in the left precuneus, manifested as young adults had more activation for recent events than for remote events, whereas no temporal distance effect was found in older adults. Interestingly, for older adults, the temporal distance effect was reflected by functional connectivity within the default mode network (DMN), with a stronger anterior DMN-posterior DMN coupling for remote events than for recent events, whereas no temporal distance difference on functional connectivity was found in young adults. The results suggest that older adults exhibit age-related neural differences in both activation and functional connectivity during the processing of autobiographical memory with different temporal distances, shedding new light for the understanding of the relationship between the DMN, autobiographical memory, and aging.
收录类别	SCI
WOS关键词	FUNCTIONAL CONNECTIVITY ; EPISODIC MEMORY ; INDEPENDENT COMPONENTS ; TIME ; PRECUNEUS ; CORTEX ; STATE ; ASSOCIATION ; VIVIDNESS ; FUTURE
WOS研究方向	Behavioral Sciences ; Neurosciences & Neurology ; Psychology
语种	英语
出版者	ACADEMIC PRESS INC ELSEVIER SCIENCE
WOS记录号	WOS:000694866100011
内容类型	期刊论文
源URL	[http://ir.psych.ac.cn/handle/311026/40269]
专题	心理研究所_中国科学院心理健康重点实验室
通讯作者	Yu, Jing
作者单位	1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing, Peoples R China 2.Southwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R China
推荐引用方式 GB/T 7714	Xu, Hong-Zhou,Xu, Xiao-Xiao,Lei, Xu,et al. Age-related alterations of default mode network in autobiographical memory: Recent versus remote events[J]. NEUROBIOLOGY OF LEARNING AND MEMORY,2021,177:8.
APA	Xu, Hong-Zhou,Xu, Xiao-Xiao,Lei, Xu,&Yu, Jing.(2021).Age-related alterations of default mode network in autobiographical memory: Recent versus remote events.NEUROBIOLOGY OF LEARNING AND MEMORY,177,8.
MLA	Xu, Hong-Zhou,et al."Age-related alterations of default mode network in autobiographical memory: Recent versus remote events".NEUROBIOLOGY OF LEARNING AND MEMORY 177(2021):8.