Determination of environmental estrogens and bisphenol A in water samples by ultra-high performance liquid chromatography coupled to Q-Exactive high resolution mass spectrometry after magnetic solid-phase extraction

doi:10.1016/j.microc.2019.104212

CORC > 成都生物研究所 > 中国科学院成都生物研究所 > 国家天然药物工程技术研究中心 > 天然产物研究

	Determination of environmental estrogens and bisphenol A in water samples by ultra-high performance liquid chromatography coupled to Q-Exactive high resolution mass spectrometry after magnetic solid-phase extraction
	Zhao, Yan 1,2,4; Bai, Xiao-Lin 4; Song, Tao 1; Zhang, Guo-Lin 4; Yuan, Yun-Cong 2,4; Liu, Yi-Ming 3,4; Liao, Xun 4
刊名	MICROCHEMICAL JOURNAL
	2019
卷号	151 页码:104212
关键词	Water Environmental estrogens Bisphenol A Fe3O4@nSiO(2)@mSiO(2)-CHO-MNPs Magnetic solid phase extraction UHPLC-Q-Exactive HRMS
ISSN号	0026-265X
DOI	10.1016/j.microc.2019.104212
产权排序	1
文献子类	Article
英文摘要	A novel, simple and rapid method based on the magnetic solid-phase extraction (MSPE) combined with ultra-high performance liquid chromatography coupled to Q-Exactive high resolution mass spectrometry (UHPLC-Q-Exactive HRMS) was developed for the determination of bisphenol A, 17 beta-estradiol, dienestrol, hexestrol, and diethylstilbestrol in water samples. In this study, novel aldehyde group functionalized core-shell mesoporous silica magnetic nanoparticles were used as adsorbents for purification and enrichment of the environmental estrogens and bisphenol A for the first time. The main factors including desorption solvent, adsorbent amount, adsorption time and desorption time affecting the performance of MSPE procedure were investigated in detail. Linearities with determination coefficients higher than 0.998 were obtained for all the target compounds, and the mean recoveries were in the range of 81.7-96.3%. The intra-day and inter-day precision were satisfactory with the relative standard deviations in the range of 2.3-8.1% and 3.5-9.9%, respectively. The limits of detection were found between 0.2 and 3.0 ng/L. Finally, the developed MSPE-UHPLC-Q-Exactive HRMS method was successfully applied for determination of the environmental estrogens and bisphenol A in water samples.
学科主题	Spectroscopy/instrumentation/analytical Sciences
URL标识	查看原文
WOS关键词	ENDOCRINE-DISRUPTING CHEMICALS ; SORPTIVE EXTRACTION ; TRACE ANALYSIS ; SURFACE-WATER ; MICROSPHERES ; NANOPARTICLES ; REMOVAL ; SHELL ; CORE ; GLUCOCORTICOIDS
WOS研究方向	Chemistry
语种	英语
出版者	ELSEVIER
WOS记录号	WOS:000497250700012
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/31129]
专题	国家天然药物工程技术研究中心_天然产物研究
作者单位	1.Sichuan Willtest Technol Co Ltd, Chengdu 610041, Sichuan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China; 3.Jackson State Univ, Dept Chem & Biochem, Jackson, MS 39217 USA; 4.Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Sichuan, Peoples R China;
推荐引用方式 GB/T 7714	Zhao, Yan,Bai, Xiao-Lin,Song, Tao,et al. Determination of environmental estrogens and bisphenol A in water samples by ultra-high performance liquid chromatography coupled to Q-Exactive high resolution mass spectrometry after magnetic solid-phase extraction[J]. MICROCHEMICAL JOURNAL,2019,151:104212.
APA	Zhao, Yan.,Bai, Xiao-Lin.,Song, Tao.,Zhang, Guo-Lin.,Yuan, Yun-Cong.,...&Liao, Xun.(2019).Determination of environmental estrogens and bisphenol A in water samples by ultra-high performance liquid chromatography coupled to Q-Exactive high resolution mass spectrometry after magnetic solid-phase extraction.MICROCHEMICAL JOURNAL,151,104212.
MLA	Zhao, Yan,et al."Determination of environmental estrogens and bisphenol A in water samples by ultra-high performance liquid chromatography coupled to Q-Exactive high resolution mass spectrometry after magnetic solid-phase extraction".MICROCHEMICAL JOURNAL 151(2019):104212.