Diterpenes from Dysoxylum lukii Merr

doi:10.1016/j.phytol.2018.09.012

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	Diterpenes from Dysoxylum lukii Merr
	Zhang, Puzhao 2; Lin, Yuan 1; Wang, Fei 1; Fang, Dongmei 1; Zhang, Guolin 1
刊名	PHYTOCHEMISTRY LETTERS
	2019
卷号	29 页码:53-56
关键词	Dysoxylum lukii Merr Meliaceae PTP-1B Diterpene Clerodane
ISSN号	1874-3900
DOI	10.1016/j.phytol.2018.09.012
产权排序	2
文献子类	Article
英文摘要	Six new diterpenes and two known compounds were isolated from the stems of Dysoxylum lukii Merr and characterized on the basis of spectral data. Dysokusone F(1), 2-Oxoneoclerod-3, 13Z-dien-15-ol (2), 3 alpha-(4-Hydroxy-3,5-dimethoxy-benzoyloxyl)-clerod-14-ene-4 beta, 13-diol (3), 3 alpha-(4-Hydroxybenzoyloxyl)-clerod-14-ene-4 beta, 13-diol (4), and 3 alpha-(4-Hydroxy-3-methoxybenzoyloxyl)-clerod-14-ene-4 beta, 13-diol (5) exhibited inhibitory effects against PTP-1B with IC50 values of 51.62 +/- 6.55, 56.74 +/- 7.96, 17.04 +/- 3.43, 28.96 +/- 4.59, and 19.70 +/- 2.57 mu M, respectively.
学科主题	Pharmacology & Toxicology
URL标识	查看原文
WOS关键词	TYROSINE-PHOSPHATASE 1B ; INHIBITORS ; STEM
WOS研究方向	Plant Sciences ; Pharmacology & Pharmacy
语种	英语
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000456346200010
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/31080]
专题	国家天然药物工程技术研究中心_天然产物研究
作者单位	1.Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Sichuan, Peoples R China 2.Jiangxi Univ Tradit Chinese Med, Nanchang 330004, Jiangxi, Peoples R China;
推荐引用方式 GB/T 7714	Zhang, Puzhao,Lin, Yuan,Wang, Fei,et al. Diterpenes from Dysoxylum lukii Merr[J]. PHYTOCHEMISTRY LETTERS,2019,29:53-56.
APA	Zhang, Puzhao,Lin, Yuan,Wang, Fei,Fang, Dongmei,&Zhang, Guolin.(2019).Diterpenes from Dysoxylum lukii Merr.PHYTOCHEMISTRY LETTERS,29,53-56.
MLA	Zhang, Puzhao,et al."Diterpenes from Dysoxylum lukii Merr".PHYTOCHEMISTRY LETTERS 29(2019):53-56.