Phylogenomic analysis demonstrates a pattern of rare and long-lasting concerted evolution in prokaryotes

doi:10.1038/s42003-018-0014-x

CORC > 成都生物研究所 > 中国科学院成都生物研究所 > 生物多样性与生态系统服务领域 > 中国科学院环境与应用微生物重点实验室

	Phylogenomic analysis demonstrates a pattern of rare and long-lasting concerted evolution in prokaryotes
	Wang, Sishuo 2,3; Chen, Youhua 1,4
刊名	COMMUNICATIONS BIOLOGY
	2018
卷号	1 页码:12
ISSN号	2399-3642
DOI	10.1038/s42003-018-0014-x
产权排序	3
文献子类	Article
英文摘要	Concerted evolution, where paralogs in the same species show higher sequence similarity to each other than to orthologs in other species, is widely found in many species. However, cases of concerted evolution that last for hundreds of millions of years are very rare. By genome-wide analysis of a broad selection of prokaryotes, we provide strong evidence of recurrent concerted evolution in 26 genes, most of which have lasted more than similar to 500 million years. We find that most concertedly evolving genes are key members of important pathways, and encode proteins from the same complexes and/or pathways, suggesting coevolution of genes via concerted evolution to maintain gene balance. We also present LRCE-DB, a comprehensive online repository of long-lasting concerted evolution. Collectively, our study reveals that although most duplicated genes may diverge in sequence over a long period, on rare occasions this constraint can be breached, leading to unexpected long-lasting concerted evolution in a recurrent manner.
URL标识	查看原文
WOS关键词	GENE CONVERSION ; DOSAGE-SENSITIVITY ; AMMONIA MONOOXYGENASE ; DEATH EVOLUTION ; DUPLICATION ; DIVERGENCE ; MECHANISM ; SELECTION ; MUTAGENESIS ; SOFTWARE
WOS研究方向	Life Sciences & Biomedicine - Other Topics ; Science & Technology - Other Topics
语种	英语
出版者	NATURE PUBLISHING GROUP
WOS记录号	WOS:000461126500012
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/30395]
专题	食品安全与环境治理领域_中国科学院环境与应用微生物重点实验室
作者单位	1.Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610000, Sichuan, Peoples R China; 2.Univ British Columbia, Fac Sci, Dept Bot, 3529-6270 Univ Blvd, Vancouver, BC V6T 1Z4, Canada; 3.Univ British Columbia, Beaty Biodivers Res Ctr, 2212 Main Mall, Vancouver, BC V6T 1Z4, Canada; 4.Univ Alberta, Fac Agr Life & Environm Sci, Dept Renewable Resources, Edmonton, AB T6G 2H1, Canada
推荐引用方式 GB/T 7714	Wang, Sishuo,Chen, Youhua. Phylogenomic analysis demonstrates a pattern of rare and long-lasting concerted evolution in prokaryotes[J]. COMMUNICATIONS BIOLOGY,2018,1:12.
APA	Wang, Sishuo,&Chen, Youhua.(2018).Phylogenomic analysis demonstrates a pattern of rare and long-lasting concerted evolution in prokaryotes.COMMUNICATIONS BIOLOGY,1,12.
MLA	Wang, Sishuo,et al."Phylogenomic analysis demonstrates a pattern of rare and long-lasting concerted evolution in prokaryotes".COMMUNICATIONS BIOLOGY 1(2018):12.