Sublethal or not? Responses of multiple biomarkers in Daphnia magna to single and joint effects of BDE-47 and BDE-209

doi:10.1016/j.ecoenv.2018.08.007

CORC > 成都生物研究所 > 中国科学院成都生物研究所 > 生物多样性与生态系统服务领域 > 中国科学院山地生态恢复与生物资源利用重点实验室

	Sublethal or not? Responses of multiple biomarkers in Daphnia magna to single and joint effects of BDE-47 and BDE-209
	Xiong, Qinli 1,2; Shi, Yajuan 2; Lu, Yonglong 2; Pan, Kaiwen 1; Dakhil, Mohammed A.1,3; Zhang, Lin 1; Xiao, Yang 2
刊名	ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
	2018
卷号	164 期号:2018 页码:164-171
关键词	Freshwater ecosystems Biomarkers Daphnia magna Mixtures toxicity PBDE congeners
ISSN号	0147-6513
DOI	10.1016/j.ecoenv.2018.08.007
产权排序	2
文献子类	Article
英文摘要	Polybrominated diphenyl ethers (PBDEs) are extremely incessant anthropogenic contaminants found in the environment, with dreadful risk to aquatic ecosystems. However, there is a limited amount of data concerning their impacts on freshwater organisms. 2,2',3,3',4,4',5,5',6,6'-decabromodiphenyl ether (BDE-209) and 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) are significant components of total PBDEs in water. The sublethal effects of BDE-47, BDE-209 and their binary mixtures on the aquatic organism Daphnia magna were investigated in acute and chronic exposure experiments. Immobilization and heartbeat were studied in daphnids after 48 h of exposure. Mortality rate, breed number, Cholinesterase (ChE), Glutathione S-transferases (GST) and Catalase (CAT) activities were evaluated after 21 days of exposure. The results showed that at 100 and 200 mu g/L concentration of BDE-47, immobilization rate of daphnids were inhibited by 44.0 +/- 16.7% and 88.0 +/- 10.9%, respectively. The binary mixture of BDE-47 and BDE-209 had uncongenial effects on immobilization of D. magna under acute toxicity test. BDE-209 significantly increased the heartbeat rate of daphnids, which increased even further when combined with BDE-47. After 21 days of exposure, daphnids exposed to single BDE-47 were physiologically altered. The combination of BDE-47 with BDE-209 significantly decreased the mortality rate of daphnids. Irrespective of the concentration, higher numbers of offsprings were produced in the mixtures compared to BDE-47 treatment alone. ChE activities significantly (p < 0.05) decreased at concentrations of 2 and 4 pg/L in single BDE-47 treatment, while GST activity significantly (p < 0.05) decreased at 0.5 g/L. CAT activities significantly increased with BDE-47 treatments in all the tested concentrations (p < 0.05). The mixtures significantly affect ChE (p < 0.05), GST (p < 0.05) and CAT activities (p < 0.05). The results illustrated that the toxicity of the mixture of PBDE congeners exposed to aquatic organisms may have antagonistic effects. The 21 days chronic test in this study suggests that acute toxicity tests, i.e. 48-h tests, using Daphnia may lead to underestimation of risks associated with PBDEs, especially, BDE-209. Hence, there is a necessity to re-examine PBDE congeners' environmental risk in aquatic organisms.
学科主题	Environment ; Ecology
URL标识	查看原文
WOS关键词	POLYBROMINATED DIPHENYL ETHERS ; BROMINATED FLAME-RETARDANT ; GLUTATHIONE S-TRANSFERASES ; BICINCHONINIC ACID ; ACETYLCHOLINESTERASE ACTIVITY ; EMBRYONIC EXPOSURE ; NEONATAL EXPOSURE ; CARASSIUS-AURATUS ; RISK-ASSESSMENT ; ADULT-MOUSE
WOS研究方向	Environmental Sciences & Ecology ; Toxicology
语种	英语
出版者	ACADEMIC PRESS INC ELSEVIER SCIENCE
WOS记录号	WOS:000449247600020
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/30621]
专题	生物多样性与生态系统服务领域_中国科学院山地生态恢复与生物资源利用重点实验室
作者单位	1.CAS Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization & Ecological Restoration Biodiversity Conservation Key Laboratory of Sichuan Province, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, PR China; 2.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Urban & Reg Ecol, Beijing 100085, Peoples R China; 3.Univ Chinese Acad Sci, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Xiong, Qinli,Shi, Yajuan,Lu, Yonglong,et al. Sublethal or not? Responses of multiple biomarkers in Daphnia magna to single and joint effects of BDE-47 and BDE-209[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,2018,164(2018):164-171.
APA	Xiong, Qinli.,Shi, Yajuan.,Lu, Yonglong.,Pan, Kaiwen.,Dakhil, Mohammed A..,...&Xiao, Yang.(2018).Sublethal or not? Responses of multiple biomarkers in Daphnia magna to single and joint effects of BDE-47 and BDE-209.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,164(2018),164-171.
MLA	Xiong, Qinli,et al."Sublethal or not? Responses of multiple biomarkers in Daphnia magna to single and joint effects of BDE-47 and BDE-209".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 164.2018(2018):164-171.