A simple and efficient synthesis protocol for sulfonation of nitrobenzene under solvent-free conditions via a microreactor

	A simple and efficient synthesis protocol for sulfonation of nitrobenzene under solvent-free conditions via a microreactor
	Chen, Yizheng 1,2; Su, Yuanhai 1; Jiao, Fengjun 1; Chen, Guangwen 1
刊名	rsc advances
	2012
卷号	2 期号:13 页码:5637-5644
通讯作者	陈光文
产权排序	1,1
英文摘要	a simple and efficient method for the sulfonation of nitrobenzene using so3 as the sulfonating agent in a microreactor was developed and conducted in this work. the reaction enthalpy was determined using a microreactor-based calorimeter. the effects of molar ratio of reactants, reaction temperature and liquid hourly space velocity (lhsv) on the reaction performance were experimentally studied under solvent-free conditions. under optimized reaction conditions, 94% conversion of nitrobenzene (nb) and 88% yield of meta-nitrobenzenesulfonic acid (m-nbsa) was obtained even when the residence time was less than 2 s. a microreactor-batch set-up was fabricated and developed to completely convert nb. the process safety has been improved and reaction time has been reduced compared to the batch method. these results demonstrate that the multifunctional integrated microreactor is an extremely useful and highly efficient tool for the sulfonation of nb under solvent-free conditions.
学科主题	物理化学
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, multidisciplinary
研究领域[WOS]	chemistry
关键词[WOS]	sulfur-trioxide sulfonation ; surfactant manufacture ; aromatic sulfonation ; mass-transfer ; reactor ; benzene ; acid ; intensification ; technology ; kinetics
收录类别	SCI
语种	英语
WOS记录号	WOS:000305274600032
公开日期	2013-10-11
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/117733]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian Natl Lab Clean Energy, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Chen, Yizheng,Su, Yuanhai,Jiao, Fengjun,et al. A simple and efficient synthesis protocol for sulfonation of nitrobenzene under solvent-free conditions via a microreactor[J]. rsc advances,2012,2(13):5637-5644.
APA	Chen, Yizheng,Su, Yuanhai,Jiao, Fengjun,&Chen, Guangwen.(2012).A simple and efficient synthesis protocol for sulfonation of nitrobenzene under solvent-free conditions via a microreactor.rsc advances,2(13),5637-5644.
MLA	Chen, Yizheng,et al."A simple and efficient synthesis protocol for sulfonation of nitrobenzene under solvent-free conditions via a microreactor".rsc advances 2.13(2012):5637-5644.