Comparative analysis of root transcriptome profiles between low- and high-cadmium-accumulating genotypes of wheat in response to cadmium stress

doi:10.1007/s10142-018-0646-4

CORC > 成都生物研究所 > 中国科学院成都生物研究所 > 食品安全与环境治理领域 > 农业生物技术研究

	Comparative analysis of root transcriptome profiles between low- and high-cadmium-accumulating genotypes of wheat in response to cadmium stress
	Zhou, Min 1,2; Zheng, Shigang 1; Liu, Rong 1,2; Lu, Jing 1,2; Lu, Lu 1; Zhang, Chihong 1; Liu, Zehou 1; Luo, Congpei 1,2; Zhang, Lei 1; Wu, Yu 1
刊名	FUNCTIONAL & INTEGRATIVE GENOMICS
	2019
卷号	19 期号:2 页码:281-294
关键词	Wheat Cadmium RNA sequencing GO-GO network Pathway-pathway network
ISSN号	1438-793X
DOI	10.1007/s10142-018-0646-4
产权排序	1
文献子类	Article
英文摘要	Wheat, one of the most broadly cultivated and consumed food crops worldwide, can accumulate high Cd contents in their edible parts, which poses a major hazard to human health. Cd accumulation ability differs among varieties in wheat, but the underlying molecular mechanism is largely unknown. Here, key genes responsible for Cd accumulation between two contrasting wheat genotypes (low-Cd accumulation one L17, high-Cd accumulation one H17) were investigated. Total 1269 were differentially expressed genes (DEGs) in L17 after Cd treatment, whereas, 399 Cd-induced DEGs were found in H17. GO-GO network analysis showed that heme binding was the most active GO, and metal binding was the second one that associated with other GOs in response to Cd stress in both genotypes. Pathway-pathway network analysis showed that phenylpronanoid biosynthesis and glutathione metabolism were the top pathways in response to Cd stress in both genotypes. Furthermore, we found that DEGs related to ion binding, antioxidant defense mechanisms, sulfotransferase activity, and cysteine biosynthetic process were more enriched in L17. In conclusion, our results not only provide the foundation for further exploring the molecular mechanism of Cd accumulation in wheat but also supply new strategies for improving phytoremediation ability of wheat by genetic engineering.
学科主题	Molecular Biology & Genetics
URL标识	查看原文
WOS关键词	L. ; CD ; IDENTIFICATION ; GROWTH ; ZINC ; PROTEOMICS ; TOLERANCE ; SEEDLINGS ; PROTEINS ; EXPOSURE
WOS研究方向	Genetics & Heredity
语种	英语
出版者	SPRINGER HEIDELBERG
WOS记录号	WOS:000459403100006
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/31002]
专题	环境治理与食品安全领域_农业生物技术研究
通讯作者	Zhou, Min
作者单位	1.Chinese Acad Sci, Chengdu Inst Biol, 9,Sect 4 South RenMin Rd, Chengdu 610041, Sichuan, Peoples R China; 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhou, Min,Zheng, Shigang,Liu, Rong,et al. Comparative analysis of root transcriptome profiles between low- and high-cadmium-accumulating genotypes of wheat in response to cadmium stress[J]. FUNCTIONAL & INTEGRATIVE GENOMICS,2019,19(2):281-294.
APA	Zhou, Min.,Zheng, Shigang.,Liu, Rong.,Lu, Jing.,Lu, Lu.,...&Wu, Yu.(2019).Comparative analysis of root transcriptome profiles between low- and high-cadmium-accumulating genotypes of wheat in response to cadmium stress.FUNCTIONAL & INTEGRATIVE GENOMICS,19(2),281-294.
MLA	Zhou, Min,et al."Comparative analysis of root transcriptome profiles between low- and high-cadmium-accumulating genotypes of wheat in response to cadmium stress".FUNCTIONAL & INTEGRATIVE GENOMICS 19.2(2019):281-294.