Diet simplification selects for high gut microbial diversity and strong fermenting ability in high-altitude pikas

doi:10.1007/s00253-018-9097-z

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	Diet simplification selects for high gut microbial diversity and strong fermenting ability in high-altitude pikas
	Li, Huan 5; Qu, Jiapeng 1; Li, Tongtong 4; Wirth, Stephan 3; Zhang, Yanming 1; Zhao, Xinquan 2; Li, Xiangzhen 2
刊名	APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
	2018-08-01
卷号	102 期号:15 页码:6739-6751
关键词	Pika Diet Gut microbiota SCFA profiles Cellulolytic activity Fermenting ability
ISSN号	0175-7598
DOI	10.1007/s00253-018-9097-z
产权排序	5
文献子类	Article
英文摘要	The gut microbiota in mammals plays a key role in host metabolism and adaptation. However, relatively little is known regarding to how the animals adapts to extreme environments through regulating gut microbial diversity and function. Here, we investigated the diet, gut microbiota, short-chain fatty acid (SCFA) profiles, and cellulolytic activity from two common pika (Ochotona spp.) species in China, including Plateau pika (Ochotona curzoniae) from the Qinghai-Tibet Plateau and Daurian pika (Ochotona daurica) from the Inner Mongolia Grassland. Despite a partial diet overlap, Plateau pikas harbored lower diet diversity than Daurian pikas. Some bacteria (e.g., Prevotella and Ruminococcus) associated with fiber degradation were enriched in Plateau pikas. They harbored higher gut microbial diversity, total SCFA concentration, and cellulolytic activity than Daurian pikas. Interestingly, cellulolytic activity was positively correlated with the gut microbial diversity and SCFAs. Gut microbial communities and SCFA profiles were segregated structurally between host species. PICRUSt metagenome predictions demonstrated that microbial genes involved in carbohydrate metabolism and energy metabolism were overrepresented in the gut microbiota of Plateau pikas. Our results demonstrate that Plateau pikas harbor a stronger fermenting ability for the plant-based diet than Daurian pikas via gut microbial fermentation. The enhanced ability for utilization of plant-based diets in Plateau pikas may be partly a kind of microbiota adaptation for more energy requirements in cold and hypoxic high-altitude environments.
学科主题	Biotechnology ; Applied Microbiology
URL标识	查看原文
WOS关键词	CHAIN FATTY-ACIDS ; RIBOSOMAL-RNA ; GASTROINTESTINAL-TRACT ; OCHOTONA-CURZONIAE ; ADAPTATION ; SEQUENCES ; METABOLISM ; RUMEN ; COMMUNITIES ; POPULATIONS
WOS研究方向	Biotechnology & Applied Microbiology
语种	英语
出版者	SPRINGER
WOS记录号	WOS:000438606100037
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/30190]
专题	成都生物研究所_应用与环境微生物研究
作者单位	1.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Adaptat & Evolut Plateau Biota, Xining 810008, Qinghai, Peoples R China; 2.Key Laboratory of Environmental and Applied Microbiology, CAS;Environmental Microbiology Key Laboratory of Sichuan Province,Chengdu Institute of Biology, Chinese Academy of Sciences,Chengdu 610041, Sichuan, People’s Republic of China 3.Inst Landscape Biogeochem, Leibniz Ctr Agr Landscape Res ZALF, Eberswalder Str 84, D-15374 Muncheberg, Germany; 4.Zhejiang Univ Technol, Coll Biotechnol & Bioengn, Dept Appl Biol, Hangzhou 310014, Zhejiang, Peoples R China; 5.Lanzhou Univ, Sch Publ Hlth, Inst Occupat Hlth & Environm Hlth, Lanzhou 730000, Gansu, Peoples R China;
推荐引用方式 GB/T 7714	Li, Huan,Qu, Jiapeng,Li, Tongtong,et al. Diet simplification selects for high gut microbial diversity and strong fermenting ability in high-altitude pikas[J]. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,2018,102(15):6739-6751.
APA	Li, Huan.,Qu, Jiapeng.,Li, Tongtong.,Wirth, Stephan.,Zhang, Yanming.,...&Li, Xiangzhen.(2018).Diet simplification selects for high gut microbial diversity and strong fermenting ability in high-altitude pikas.APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,102(15),6739-6751.
MLA	Li, Huan,et al."Diet simplification selects for high gut microbial diversity and strong fermenting ability in high-altitude pikas".APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 102.15(2018):6739-6751.