The extremely large chloroplast genome of the green alga Haematococcus pluvialis: Genome structure, and comparative analysis

doi:10.1016/j.algal.2021.102308

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室 > 海岸带生物学与生物资源利用所重点实验室

	The extremely large chloroplast genome of the green alga Haematococcus pluvialis: Genome structure, and comparative analysis
	Ren, Qingmin 1,2; Wang, Yin-chu 1,3; Lin, Yanni 4; Zhen, Zhanghe 1,2; Cui, Yulin 1,3; Qin, Song 1,3
刊名	ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
	2021-06-01
卷号	56 页码:11
关键词	Haematococcus pluvialis Chloroplast genome Astaxanthin Non-coding regions Repeated sequences
ISSN号	2211-9264
DOI	10.1016/j.algal.2021.102308
通讯作者	Qin, Song(sqin@yic.ac.cn)
英文摘要	Astaxanthin is arguably nature's most potent antioxidant, powerful to prevent free radical damage and oxidative stress. The microalga Haematococcus pluvialis seems to accumulate the highest levels of astaxanthin in nature and thus is currently the primary industrial source for natural astaxanthin production. The accumulation happens under photooxidative stress to quench radical damage from the photosynthesis, which is considered as one of the main reasons why chloroplast genomes are usually kept the small size and high guanine-cytosine (GC) content. We hypothesize that the outstanding astaxanthin production of the species may reflect its chloroplast genome features. In this study, the complete chloroplast genome of H. pluvialis FACHB-712 was sequenced and investigated. The genome is large, comprising 1.35 Mbp with 83 genes. However, the GC content is counterintuitively as high as 50.1%. The genome shows slight phylogenetic distance and genome structural differences in comparison with that of H. lacustris, whose species nomenclature is confusing and controversial. Moreover, a possible correlation between its powerful antioxidant capacity and the large chloroplast genome maintenance was further investigated. Strains of Chlorophyta and several strains with chloroplast genomes size of more than 500 kbp were used for comparative analysis. The evolutionary mechanism for the large chloroplast genome and and the contribution of non-coding region ratio and GC content to genome amplification is discussed.Large genomes may be associated with harsh habitats, and increased GC content may be used to increase stability.
资助项目	National Natural Science Foundation of China[41876188] ; Major Basic Research Program of Shandong Province Natural Science Foundation[ZR2018ZB0210] ; Project of Innovation & Development of Marine Economy[HHCL201803]
WOS关键词	NOV RHODELLOPHYCEAE ; PLASTID GENOMES ; CHLOROPHYCEAE ; SEQUENCE ; MITOCHONDRIAL ; ORGANELLE ; GENES ; ARCHITECTURE ; REPLICATION ; INSTABILITY
WOS研究方向	Biotechnology & Applied Microbiology
语种	英语
WOS记录号	WOS:000663410100004
资助机构	National Natural Science Foundation of China ; Major Basic Research Program of Shandong Province Natural Science Foundation ; Project of Innovation & Development of Marine Economy
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/29427]
专题	烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
通讯作者	Qin, Song
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resource Utilizat, Yantai 264003, Shandong, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Peoples R China 4.Yantai Univ, Yantai 264005, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Ren, Qingmin,Wang, Yin-chu,Lin, Yanni,et al. The extremely large chloroplast genome of the green alga Haematococcus pluvialis: Genome structure, and comparative analysis[J]. ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS,2021,56:11.
APA	Ren, Qingmin,Wang, Yin-chu,Lin, Yanni,Zhen, Zhanghe,Cui, Yulin,&Qin, Song.(2021).The extremely large chloroplast genome of the green alga Haematococcus pluvialis: Genome structure, and comparative analysis.ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS,56,11.
MLA	Ren, Qingmin,et al."The extremely large chloroplast genome of the green alga Haematococcus pluvialis: Genome structure, and comparative analysis".ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 56(2021):11.