Dunaliella salina is a halophilic green microalgae enriched with β-carotene. With the further study of Dunaliella sali na, its carotenoid metabolism pathway has become quite clear. Dunaliella salina, as the raw material for health care, has been put into industrial production. In recent years, bioreactor has become a hot topic of biotechnology research in the world. Dunaliella salina, as a bioreactor, has considerable potential for development. This paper mainly summarizes the research progress of the pathway of carote noid metabolism in Dunaliella salina, development and application prospects of bioreactor, existing problems.