Intrinsic plasticity (IP) mechanism was originally found in the biological neuron as a membrane potential adaptive tuning scheme, which was used to change the connection strength between neurons, so that animal brain had the ability to learn or store memory. Recently, in the field of artificial neural networks, the bio-inspired IP mechanism attracts increasingly research attention due to its ability of regulating neuron activity in a relative homeostatic level even if the external input of a neuron is extremely low or extremely high and tuning the probability density of a neuron's output toward an exponential distribution, thereby realizing information maximization. In this paper, the IP mechanism was applied to the spiking neuron model-based multi-layer perceptrons (Spiking MLPs). The experiment results showed that compared with the networks without IP, both the convergence speed and the robustness of computation accuracy were effectively improved.