Characterization of flounder (Paralichthys olivaceus) FoxD5 and its function in regulating myogenic regulatory factor

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	Characterization of flounder (Paralichthys olivaceus) FoxD5 and its function in regulating myogenic regulatory factor
	Tan Xungang1 ; Zhang Yuqing 1,2; Sun Wei 1,2; Zhang Peijun 1; Xu Yongli 1
刊名	CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY
	2012-03-01
卷号	30 期号:2 页码:286-294
关键词	flounder FoxD5 muscle over-expression in situ hybridization myogenic regulatory factor
ISSN号	0254-4059
通讯作者	Tan, XG (reprint author), Chinese Acad Sci, Inst Oceanol, EMBLC, Qingdao 266071, Peoples R China.
英文摘要	As one member of winged helix domain transcription factors, FoxD5 was reported to be a trunk organizer. Recent study showed that zebrafish foxd5 is expressed in the somites. To further understand the function of FoxD5 in fish muscle development, the FoxD5 gene was isolated from flounder. Its expression pattern was analyzed by in situ hybridization, while its function in regulating myogenic regulatory factor, MyoD, was analyzed by ectopic expression. It showed that flounder FoxD5 was firstly expressed in the tailbud, adaxial cells, and neural plate of the head. In flounder embryo, FoxD5 is expressed not only in forebrain but also in somite cells that will form muscle in the future. When flounder FoxD5 was over-expressed in zebrafish by microinjection, the expression of zebrafish MyoD in the somites was reduced, suggesting that FoxD5 is involved in myogenesis by regulating the expression of MyoD.
学科主题	Limnology ; Oceanography
收录类别	SCI
原文出处	10.1007/s00343-012-1080-4
语种	英语
WOS记录号	WOS:000301001900013
公开日期	2013-09-24
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/12297]
专题	海洋研究所_实验海洋生物学重点实验室
作者单位	1.Chinese Acad Sci, Inst Oceanol, EMBLC, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Tan Xungang,Zhang Yuqing,Sun Wei,et al. Characterization of flounder (Paralichthys olivaceus) FoxD5 and its function in regulating myogenic regulatory factor[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2012,30(2):286-294.
APA	Tan Xungang,Zhang Yuqing,Sun Wei,Zhang Peijun,&Xu Yongli.(2012).Characterization of flounder (Paralichthys olivaceus) FoxD5 and its function in regulating myogenic regulatory factor.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,30(2),286-294.
MLA	Tan Xungang,et al."Characterization of flounder (Paralichthys olivaceus) FoxD5 and its function in regulating myogenic regulatory factor".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 30.2(2012):286-294.