Asperolides A-C, Tetranorlabdane Diterpenoids from the Marine Alga-Derived Endophytic Fungus Aspergillus wentii EN-48

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	Asperolides A-C, Tetranorlabdane Diterpenoids from the Marine Alga-Derived Endophytic Fungus Aspergillus wentii EN-48
	Sun, Hao-Fen 2,3; Li, Xiao-Ming 2; Meng, Li 1; Cui, Chuan-Ming 2,3; Gao, Shu-Shan 2,3; Li, Chun-Shun 2; Huang, Cai-Guo 1; Wang, Bin-Gui2
刊名	JOURNAL OF NATURAL PRODUCTS
	2012-02-01
卷号	75 期号:2 页码:148-152
关键词	PENICILLIUM-CHRYSOGENUM QEN-24S NORDITERPENE DILACTONES CHAETOMIUM-GLOBOSUM ANTIFUNGAL METABOLITES OCHRACEUS ALKALOIDS CHEMISTRY STEROIDS AGENTS
ISSN号	0163-3864
通讯作者	Huang, CG (reprint author), Mil Med Coll 2, Dept Biochem & Mol Biol, Xiangyin Rd 800, Shanghai 200433, Peoples R China.
英文摘要	Bioassay-guided fractionation of the culture extract of Aspergillus wentii EN-48, an endophytic fungus isolated from an unidentified marine brown algal species of the genus Sargassum, led to the isolation of three new tetranorlabdane diterpenoids, asperolides A-C (1-3), and five related derivatives (4-8). The structures of these compounds were established on the basis of spectroscopic interpretation, and compound 1 was confirmed by X-ray crystallographic analysis. The absolute configuration of I was determined by application of the modified Mosher's method. An Xray structure for wentilactone B (6) is also reported. Compounds 1-8 were evaluated for cytotoxic and antibacterial activities.
学科主题	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
收录类别	SCI ; IC
原文出处	10.1021/np2006742
语种	英语
WOS记录号	WOS:000300601500006
公开日期	2013-09-24
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/12286]
专题	海洋研究所_实验海洋生物学重点实验室
作者单位	1.Second Mil Med Univ, Dept Biochem & Mol Biol, Shanghai 200433, Peoples R China 2.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Sun, Hao-Fen,Li, Xiao-Ming,Meng, Li,et al. Asperolides A-C, Tetranorlabdane Diterpenoids from the Marine Alga-Derived Endophytic Fungus Aspergillus wentii EN-48[J]. JOURNAL OF NATURAL PRODUCTS,2012,75(2):148-152.
APA	Sun, Hao-Fen.,Li, Xiao-Ming.,Meng, Li.,Cui, Chuan-Ming.,Gao, Shu-Shan.,...&Wang, Bin-Gui.(2012).Asperolides A-C, Tetranorlabdane Diterpenoids from the Marine Alga-Derived Endophytic Fungus Aspergillus wentii EN-48.JOURNAL OF NATURAL PRODUCTS,75(2),148-152.
MLA	Sun, Hao-Fen,et al."Asperolides A-C, Tetranorlabdane Diterpenoids from the Marine Alga-Derived Endophytic Fungus Aspergillus wentii EN-48".JOURNAL OF NATURAL PRODUCTS 75.2(2012):148-152.