A new method for the synthesis of chalcone derivatives promoted by PPh3/I(2)under non-alkaline conditions

doi:10.1080/00397911.2020.1847295

	A new method for the synthesis of chalcone derivatives promoted by PPh3/I(2)under non-alkaline conditions
	Xue, Kangsheng 3; Sun, Guoxiang 4; Zhang, Yanzhi 1; Chen, Xubing 1; Zhou, Yang 2,5; Hou, Jinjun 2,5; Long, Huali 2,5; Zhang, Zijia 2,5; Lei, Min 2,5; Wu, Wanying 2,5
刊名	SYNTHETIC COMMUNICATIONS
	2020-11-19
页码	10
关键词	Aldehyde chalcone Claisen-Schmidt reaction ketone PPh3 I2
ISSN号	0039-7911
DOI	10.1080/00397911.2020.1847295
通讯作者	Lei, Min(mlei@simm.ac.cn) ; Wu, Wanying(wanyingwu@simm.ac.cn)
英文摘要	A straightforward and general method has been developed for the synthesis of chalcone derivatives by a Claisen-Schmidt reaction in the presence of PPh3/I-2 in 1,4-dioxane under reflux temperatures. With the condensation of the aromatic ketone and aldehyde occurring at non-strongly alkaline conditions, our proposed method significantly expands the range of applicable substrates, especially for groups that are unstable under alkaline conditions.
资助项目	Special Fund for Strategic Pilot Technology of the Chinese Academy of Sciences[XDA12020379] ; National Natural Science Foundation of China[81973455] ; National Key R&D Program of China[2018YFC1707900]
WOS关键词	SOLVENT-FREE CONDITIONS ; EFFICIENT SYNTHESIS ; HETEROGENEOUS CATALYST ; BIOLOGICAL EVALUATION ; ALDOL CONDENSATIONS ; DESIGN ; AGENTS ; FLAVONOIDS ; INHIBITORS ; AMIDATION
WOS研究方向	Chemistry
语种	英语
出版者	TAYLOR & FRANCIS INC
WOS记录号	WOS:000590637100001
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/292692]
专题	中国科学院上海药物研究所
通讯作者	Lei, Min; Wu, Wanying
作者单位	1.Dali Univ, Coll Pharm, Dali, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Changchun Univ Chinese Med, Coll Pharm, Changchun, Peoples R China 4.Yancheng Inst Technol, Sch Chem & Chem Engn, Yancheng, Jiangsu, Peoples R China 5.Chinese Acad Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai Inst Mat Med, Natl Engn Lab TCM Standardizat Technol, Shanghai, Peoples R China
推荐引用方式 GB/T 7714	Xue, Kangsheng,Sun, Guoxiang,Zhang, Yanzhi,et al. A new method for the synthesis of chalcone derivatives promoted by PPh3/I(2)under non-alkaline conditions[J]. SYNTHETIC COMMUNICATIONS,2020:10.
APA	Xue, Kangsheng.,Sun, Guoxiang.,Zhang, Yanzhi.,Chen, Xubing.,Zhou, Yang.,...&Wu, Wanying.(2020).A new method for the synthesis of chalcone derivatives promoted by PPh3/I(2)under non-alkaline conditions.SYNTHETIC COMMUNICATIONS,10.
MLA	Xue, Kangsheng,et al."A new method for the synthesis of chalcone derivatives promoted by PPh3/I(2)under non-alkaline conditions".SYNTHETIC COMMUNICATIONS (2020):10.