Rh(III)-Catalyzed Dual C-H Functionalization/Cyclization Cascade by a Removable Directing Group: A Method for Synthesis of Polycyclic Fused Pyrano[de]Isochromenes

doi:10.1021/acs.joc.0c01228

	Rh(III)-Catalyzed Dual C-H Functionalization/Cyclization Cascade by a Removable Directing Group: A Method for Synthesis of Polycyclic Fused Pyrano[de]Isochromenes
	Shu, Zhihao 1,2,3; Zhou, Jianhui 2,3; Li, Junyou 2,3; Cheng, Yilang 2,3; Liu, Hong 1,2,3; Wang, Dechuan 1; Zhou, Yu 2,3
刊名	JOURNAL OF ORGANIC CHEMISTRY
	2020-10-02
卷号	85 期号:19 页码:12097-12107
ISSN号	0022-3263
DOI	10.1021/acs.joc.0c01228
通讯作者	Wang, Dechuan(wdc@cpu.edu.cn) ; Zhou, Yu(zhouyu@simm.ac.cn)
英文摘要	An interesting Rh(III)-catalyzed dual C-H functionalization/cyclization cascade of azomethine imine with diazophosphonate by a removable directing group for the synthesis of highly fused pyrano[de]isochromene has been achieved. The transformation shows that the desired pyrano[de]isochromenes with two oxygen atoms on its core scaffold could be constructed with good to excellent yields (up to 86%) via a facile one-pot, multiple-step cascade reaction, along with broad generality and versatility.
资助项目	National Natural Science Foundation of China[21672232] ; National Natural Science Foundation of China[21632008] ; National Natural Science Foundation of China[81620108027] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDA12040217]
WOS关键词	RELAY CARBENOID FUNCTIONALIZATION ; DIAZO-COMPOUNDS ; BOND ACTIVATION ; MORUS-ALBA ; CYCLIZATION ; ACCESS ; ACTIVATION/CYCLIZATION ; BENZAMIDES ; SYNTHONS
WOS研究方向	Chemistry
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000577156600009
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/291422]
专题	中国科学院上海药物研究所
通讯作者	Wang, Dechuan; Zhou, Yu
作者单位	1.China Pharmaceut Univ, Sch Sci, Nanjing 211198, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, Key Lab Receptor Res, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Shu, Zhihao,Zhou, Jianhui,Li, Junyou,et al. Rh(III)-Catalyzed Dual C-H Functionalization/Cyclization Cascade by a Removable Directing Group: A Method for Synthesis of Polycyclic Fused Pyrano[de]Isochromenes[J]. JOURNAL OF ORGANIC CHEMISTRY,2020,85(19):12097-12107.
APA	Shu, Zhihao.,Zhou, Jianhui.,Li, Junyou.,Cheng, Yilang.,Liu, Hong.,...&Zhou, Yu.(2020).Rh(III)-Catalyzed Dual C-H Functionalization/Cyclization Cascade by a Removable Directing Group: A Method for Synthesis of Polycyclic Fused Pyrano[de]Isochromenes.JOURNAL OF ORGANIC CHEMISTRY,85(19),12097-12107.
MLA	Shu, Zhihao,et al."Rh(III)-Catalyzed Dual C-H Functionalization/Cyclization Cascade by a Removable Directing Group: A Method for Synthesis of Polycyclic Fused Pyrano[de]Isochromenes".JOURNAL OF ORGANIC CHEMISTRY 85.19(2020):12097-12107.