Synthesis of indolo[2,3-c]coumarins and indolo[2,3-c]quinolinones via microwave-assisted base-free intramolecular cross dehydrogenative coupling

doi:10.1016/j.tet.2018.11.066

	Synthesis of indolo[2,3-c]coumarins and indolo[2,3-c]quinolinones via microwave-assisted base-free intramolecular cross dehydrogenative coupling
	Gu, Chang-Xue 1,2; Chen, Wen-Wen 1; Xu, Bin 2; Xu, Ming-Hua 1
刊名	TETRAHEDRON
	2019-03-22
卷号	75 期号:12 页码:1605-1611
关键词	Indolo[2,3-c]coumarin Indolo[2,3-c]quinolinone Palladium Cross dehydrogenative coupling Microwave-assisted synthesis Fused polyheterocycles
ISSN号	0040-4020
DOI	10.1016/j.tet.2018.11.066
通讯作者	Chen, Wen-Wen(wenwen@simm.ac.cn) ; Xu, Ming-Hua(xumh@simm.ac.cn)
英文摘要	A microwave-assisted base-free intramolecular cross dehydrogenative coupling (CDC) of 3-aniline substituted coumarins and quinolinones have been developed. A broad range of indolo[2,3-c]coumarins and indolo[2,3-c]quinolinones can be easily afforded in good to high yields (up to 93%) under palladium catalysis. The method is among the most straightforward and convenient ways to access these fused polyheterocycles. (C) 2018 Elsevier Ltd. All rights reserved.
资助项目	National Natural Science Foundation of China[21472205] ; National Natural Science Foundation of China[81521005] ; National Natural Science Foundation of China[21325209] ; Shanghai Municipal Committee of Science and Technology[18ZR1447600] ; SA-SIBS Scholarship Program
WOS关键词	RESISTANCE REVERSAL ACTIVITY ; MULTIDRUG-RESISTANCE ; LAMELLARIN-D ; BENZOPYRANONES ; CONSTRUCTION ; ALKALOIDS ; NINGALINS ; ANALOGS ; ACCESS
WOS研究方向	Chemistry
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000462418900006
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/290190]
专题	中国科学院上海药物研究所
通讯作者	Chen, Wen-Wen; Xu, Ming-Hua
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China 2.Shanghai Univ, Innovat Drug Res Ctr, Dept Chem, Shanghai 200444, Peoples R China
推荐引用方式 GB/T 7714	Gu, Chang-Xue,Chen, Wen-Wen,Xu, Bin,et al. Synthesis of indolo[2,3-c]coumarins and indolo[2,3-c]quinolinones via microwave-assisted base-free intramolecular cross dehydrogenative coupling[J]. TETRAHEDRON,2019,75(12):1605-1611.
APA	Gu, Chang-Xue,Chen, Wen-Wen,Xu, Bin,&Xu, Ming-Hua.(2019).Synthesis of indolo[2,3-c]coumarins and indolo[2,3-c]quinolinones via microwave-assisted base-free intramolecular cross dehydrogenative coupling.TETRAHEDRON,75(12),1605-1611.
MLA	Gu, Chang-Xue,et al."Synthesis of indolo[2,3-c]coumarins and indolo[2,3-c]quinolinones via microwave-assisted base-free intramolecular cross dehydrogenative coupling".TETRAHEDRON 75.12(2019):1605-1611.