enantiomericpairsofmeroterpenoidsfromrhododendronfastigiatum

	enantiomericpairsofmeroterpenoidsfromrhododendronfastigiatum
	Huang Guanghui 1; Lei Chun 1; Zhu Kexin 2; Li Jingya 2; Li Jia 2; Hou Aijun 1
刊名	chinesejournalofnaturalmedicines
	2019
卷号	17 期号:12 页码:963
关键词	Meroterpenoid enantiomers Protein tyrosine phosphatase 1B
ISSN号	1875-5364
英文摘要	Five pairs of optically pure meroterpenoid enantiomers ( 1a - 5a ) and two known compounds ( 6 and 7 ) were isolated from Rhododendron fastigiatum . Compounds 1a - 5a were resolved from naturally scalemic mixtures by chiral HPLC. Their structures were elucidated by spectroscopic methods, X-ray crystallographic experiments, and ECD analyses. Compounds 1a , 2a , 3b , 4a , and 5a were new meroterpenoids with different polycyclic systems. Two enantiomeric pairs ( 2a and 3a ), 6 , and 7 exhibited inhibitory effects on protein tyrosine phosphatase 1B (PTP1B) in vitro .
语种	英语
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/280729]
专题	中国科学院上海药物研究所
作者单位	1.复旦大学 2.中国科学院上海药物研究所
推荐引用方式 GB/T 7714	Huang Guanghui,Lei Chun,Zhu Kexin,et al. enantiomericpairsofmeroterpenoidsfromrhododendronfastigiatum[J]. chinesejournalofnaturalmedicines,2019,17(12):963.
APA	Huang Guanghui,Lei Chun,Zhu Kexin,Li Jingya,Li Jia,&Hou Aijun.(2019).enantiomericpairsofmeroterpenoidsfromrhododendronfastigiatum.chinesejournalofnaturalmedicines,17(12),963.
MLA	Huang Guanghui,et al."enantiomericpairsofmeroterpenoidsfromrhododendronfastigiatum".chinesejournalofnaturalmedicines 17.12(2019):963.