Facile synthesis of new functionalized 3,4-dihydro-2H-pyrroles using 2-isocyanoacetates | |
Zhang, Huijie1,2; Lv, Kaikai1,2; Ma, Lanping2; Zhang, Yongliang2; Yu, Ting2; Chen, Lin2; Wang, Xin2; Shen, Jingkang2; Meng, Tao1,2 | |
刊名 | TETRAHEDRON LETTERS |
2020-06-04 | |
卷号 | 61期号:23页码:5 |
关键词 | 3,4-Dihydro-2H-pyrroles 2-Isocyanoacetates (E)-2-Styrylbenzothiazole Acrylonitriles |
ISSN号 | 0040-4039 |
DOI | 10.1016/j.tetlet.2020.151944 |
通讯作者 | Meng, Tao(tmeng@simm.ac.cn) |
英文摘要 | A one-step synthesis of novel functionalized 3,4-dihydro-2H-pyrroles from 2-isocyanoacetates and readily synthesized acrylonitriles is reported. The reaction proceeds smoothly under mild conditions with high efficiency. The structures of two representative structures, 3a and 3m, were confirmed by X-ray crystallographic analysis. (C) 2020 Elsevier Ltd. All rights reserved. |
资助项目 | National Science & Technology Major Project Key New Drug Creation and Manufacturing Program, China[2014ZX09508001] ; National Natural Science Foundation of China[81473130] ; National Natural Science Foundation of China[81473092] |
WOS关键词 | POT SEQUENTIAL SYNTHESIS ; ENANTIOSELECTIVE SYNTHESIS ; 3-COMPONENT ; PYRROLES ; CYCLOADDITION ; HETEROCYCLES ; 3,4-DIARYL |
WOS研究方向 | Chemistry |
语种 | 英语 |
出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
WOS记录号 | WOS:000535721300008 |
内容类型 | 期刊论文 |
源URL | [http://119.78.100.183/handle/2S10ELR8/280126] |
专题 | 中国科学院上海药物研究所 |
通讯作者 | Meng, Tao |
作者单位 | 1.Univ Chinese Acad Sci, Sch Pharm, 19A Yuquan Rd, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Huijie,Lv, Kaikai,Ma, Lanping,et al. Facile synthesis of new functionalized 3,4-dihydro-2H-pyrroles using 2-isocyanoacetates[J]. TETRAHEDRON LETTERS,2020,61(23):5. |
APA | Zhang, Huijie.,Lv, Kaikai.,Ma, Lanping.,Zhang, Yongliang.,Yu, Ting.,...&Meng, Tao.(2020).Facile synthesis of new functionalized 3,4-dihydro-2H-pyrroles using 2-isocyanoacetates.TETRAHEDRON LETTERS,61(23),5. |
MLA | Zhang, Huijie,et al."Facile synthesis of new functionalized 3,4-dihydro-2H-pyrroles using 2-isocyanoacetates".TETRAHEDRON LETTERS 61.23(2020):5. |
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