Synthesis and Antibacterial Activity of Oxazolidinone Derivatives Containing Nitro Heteroaromatic Moiety

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	Synthesis and Antibacterial Activity of Oxazolidinone Derivatives Containing Nitro Heteroaromatic Moiety
	Xu Boxuan 2; Ding Xiudong 1; Wu Yachuang 2; Cui Lei 1; Qian Ping 2; Wang Di 1; Zhao Yanfang 2
刊名	CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
	2018
卷号	34 期号:1 页码:51-56
关键词	AGENTS DISCOVERY SAR Oxazolidinone derivative Antibacterial activity Linezolid Ranbezolid
ISSN号	1005-9040
其他题名	Synthesis and Antibacterial Activity of Oxazolidinone Derivatives Containing Nitro Heteroaromatic Moiety
英文摘要	A series of novel oxazolidinone derivatives containing nitro heteroaromatic moiety was synthesized and characterized by means of H-1 NMR and MS spectra. All target compounds were evaluated for their in vitro antibacterial activities against S.au 29213, methicillin-resistant Staphylococcus aureus(MRSA) and vancomycin-resistant Enterococcus(VRE) by minimum inhibitory concentration(MIC) assay. Most of them exhibited antibacterial activity against S. au 29213, MRSA and VRE. Among them, compounds 10e and 10f displayed better activity than the control.
资助项目	[Program for Innovative Research Team of the Ministry of Education of China] ; [Program for Liaoning Innovative Research Team in University, China] ; [Basic Program of Liaoning Provincial Department of Education, China]
语种	英语
CSCD记录号	CSCD:6163249
内容类型	期刊论文
源URL	[http://ir.imr.ac.cn/handle/321006/148313]
专题	金属研究所_中国科学院金属研究所
作者单位	1.309th Hosp PLA, Department Clin Lab, Beijing 100091, Peoples R China 2.中国科学院金属研究所
推荐引用方式 GB/T 7714	Xu Boxuan,Ding Xiudong,Wu Yachuang,et al. Synthesis and Antibacterial Activity of Oxazolidinone Derivatives Containing Nitro Heteroaromatic Moiety[J]. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,2018,34(1):51-56.
APA	Xu Boxuan.,Ding Xiudong.,Wu Yachuang.,Cui Lei.,Qian Ping.,...&Zhao Yanfang.(2018).Synthesis and Antibacterial Activity of Oxazolidinone Derivatives Containing Nitro Heteroaromatic Moiety.CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,34(1),51-56.
MLA	Xu Boxuan,et al."Synthesis and Antibacterial Activity of Oxazolidinone Derivatives Containing Nitro Heteroaromatic Moiety".CHEMICAL RESEARCH IN CHINESE UNIVERSITIES 34.1(2018):51-56.