Clinical significance of the expression of inducible nitric oxide synthase in non-small cell lung cancer

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	Clinical significance of the expression of inducible nitric oxide synthase in non-small cell lung cancer
	Yang Chunlu 1; Wang Yong 2; Zhao Jun 1; Zhang Yiliang 1
刊名	CHINESE JOURNAL OF CANCER RESEARCH
	2007
卷号	19 期号:2 页码:136-140
关键词	ANGIOGENESIS APOPTOSIS HYPOXIA MICE NSCLC iNOS prognosis
ISSN号	1000-9604
其他题名	Clinical Significance of the Expression of Inducible Nitric Oxide Synthase in Non-Small Cell Lung Cancer
英文摘要	Objective: To study the expressive characteristics of iNOS in non-small cell lung carcinoma (NSCLC) and it's affection to the prognosis NSCLC patients. Methods: The expression of iNOS was detected in 50 NSCLC tissues by Immunohistochemistry technology. Results: There was positive expression in NSCLC ( positive rate 38.00%). The expression of iNOS had a correlation with lymph node metastasis (P 0.05). But the data suggested that there was a direct correlation between expression of iNOS and clinical prognosis (P < 0.05). Conclusion: Positive expression of iNOS was observed in NSCLC, which correlated with postoperative survival time and lymph node metastasis. Although iNOS level had no significant relation with T stage, we find the positive rate in T2 stage was much higher than that in T1 stage. The result suggested that positive expression of iNOS was related to bad clinical prognosis because of promoting tumor growth and metastasis.
语种	英语
CSCD记录号	CSCD:2911742
内容类型	期刊论文
源URL	[http://ir.imr.ac.cn/handle/321006/146172]
专题	金属研究所_中国科学院金属研究所
作者单位	1.中国科学院金属研究所 2.Benxi Steel Co, Gen Hosp, Department Thorac Surg, Benxi 117000, Peoples R China
推荐引用方式 GB/T 7714	Yang Chunlu,Wang Yong,Zhao Jun,et al. Clinical significance of the expression of inducible nitric oxide synthase in non-small cell lung cancer[J]. CHINESE JOURNAL OF CANCER RESEARCH,2007,19(2):136-140.
APA	Yang Chunlu,Wang Yong,Zhao Jun,&Zhang Yiliang.(2007).Clinical significance of the expression of inducible nitric oxide synthase in non-small cell lung cancer.CHINESE JOURNAL OF CANCER RESEARCH,19(2),136-140.
MLA	Yang Chunlu,et al."Clinical significance of the expression of inducible nitric oxide synthase in non-small cell lung cancer".CHINESE JOURNAL OF CANCER RESEARCH 19.2(2007):136-140.