Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate

doi:10.11900/0412.1961.2017.00285

CORC > 金属研究所 > 中国科学院金属研究所

	Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate
	Yu Xiaoming 1; Tan Lili 1; Liu Zongyuan 1; Yang Ke 1; Zhu Zhonglin 2; Li Yangde 3
刊名	ACTA METALLURGICA SINICA
	2018-06-01
卷号	54 期号:6 页码:943-949
关键词	Ti alloy pure Mg coating bioproperty
ISSN号	0412-1961
DOI	10.11900/0412.1961.2017.00285
通讯作者	Tan Lili(lltan@imr.ac.cn)
英文摘要	Currently, metallic biomaterials used in orthopedics are normally bioinert which is hard to integrate with the bone tissue inducing aseptic loosening and easy to get infection, which is the main reason of implantation failure. Mg base metals are considered to be a new generation of revolutionary metallic biomaterials due to its similar density and mechanical properties with natural bone, good biocompatibility, degradability in the body as well as the biological functional ability to promote new bone tissue formation. In addition, the degradation of Mg may increase the local pH which can inhibit the growth of bacteria. In this work, pure Mg coating was deposited on Ti6Al4V substrate by arc ion plating. The effects of different working pressures on the surface quality and properties of Mg coating were investigated. The degradation, antibacterial and biosafety properties were studyied. The results showed that the pure Mg coating can be deposited on the surface of Ti6Al4V substrate and the coating was uniform and smooth. The immersion test in vitro showed that the degradation was very fast because of galvanic corrosion, and the whole process was finished in about one week. The results of antimicrobial experiments showed that the Mg coating can kill staphylococcus aureus and showed good antibacterial function. The results of cytotoxicity test showed that Mg coating promoted rabbit bone marrow mesenchymal stem cells (rBMSCs) growth and proliferation.
资助项目	National Natural Science Foundation of China[51631009] ; National Natural Science Foundation of China[81500897] ; National Natural Science Foundation of China[81400528] ; National Key Research and Development Program of China[2016YFC1101804]
WOS研究方向	Metallurgy & Metallurgical Engineering
语种	英语
出版者	SCIENCE PRESS
WOS记录号	WOS:000433007400014
资助机构	National Natural Science Foundation of China ; National Key Research and Development Program of China
内容类型	期刊论文
源URL	[http://ir.imr.ac.cn/handle/321006/128468]
专题	金属研究所_中国科学院金属研究所
通讯作者	Tan Lili
作者单位	1.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China 2.Jiangsu OKANI Med Technol Co Ltd, Suzhou 215123, Peoples R China 3.Dong Guan EONTC Co Ltd, Dongguan 523808, Peoples R China
推荐引用方式 GB/T 7714	Yu Xiaoming,Tan Lili,Liu Zongyuan,et al. Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate[J]. ACTA METALLURGICA SINICA,2018,54(6):943-949.
APA	Yu Xiaoming,Tan Lili,Liu Zongyuan,Yang Ke,Zhu Zhonglin,&Li Yangde.(2018).Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate.ACTA METALLURGICA SINICA,54(6),943-949.
MLA	Yu Xiaoming,et al."Preparation and Properties of Biological Functional Magnesium Coating on Ti6Al4V Substrate".ACTA METALLURGICA SINICA 54.6(2018):943-949.