Critical-Size Defects of Animal Models for Bone Regeneration

doi:10.1166/jbt.2018.1821

CORC > 兰州化学物理研究所 > 中国科学院兰州化学物理研究所 > 固体润滑国家重点实验室

	Critical-Size Defects of Animal Models for Bone Regeneration
	Lv, Zhao-Yong 2; Chen, Xi-Meng 3; Zhang, Yu-Jue 2; Li, June 2; Zhao, Zhong-Hui 2; Li, Ke-Yi 2; Xie, Guan-Nan 2; Liu, Feng-Zhen 1,2; Zhang, Bin 2
刊名	JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING
	2018-06-01
卷号	8 期号:6 页码:761-770
关键词	Critical-Size Defects Animal Models Bone Regeneration Review
ISSN号	2157-9083
DOI	10.1166/jbt.2018.1821
通讯作者	Xie, Guan-Nan() ; Liu, Feng-Zhen() ; Zhang, Bin()
英文摘要	Animal models have been extensively used and have contributed greatly to the development and establishment of a wide range of translational approaches aiming to regenerate the bone tissue. Accordingly, this paper presents a review of the critical-size defects (CSDs) of animal models for bone repair and contributes to determine which defect dimensions could be considered as being critical size. Recent work involving the definition of CSDs, CSDs related animal models for bone regeneration, and an overview of the evaluation of bone regeneration in the critical size defects has been summarized and reviewed. A systematic review were conducted to provide prerequisite data for establishing bone critical size defect model in different animals and evaluating bone materials using these models and guide future clinical trials of bone tissue engineering, more importantly, determine the estimates and the effect for guiding future human clinical trials. Also, there is a necessity for further standardization of the animal models to enable more accurate comparison among future studies.
资助项目	Science Foundation of Shandong Province of China[ZR2017PH056] ; Science Foundation of Shandong Province of China[ZR2017PH037] ; Medicine and health Science technology development plan of Shandong Province of China[2017WS503]
WOS研究方向	Cell Biology
语种	英语
出版者	AMER SCIENTIFIC PUBLISHERS
资助机构	Science Foundation of Shandong Province of China ; Medicine and health Science technology development plan of Shandong Province of China
内容类型	期刊论文
源URL	[http://ir.licp.cn/handle/362003/27212]
专题	兰州化学物理研究所_固体润滑国家重点实验室
通讯作者	Xie, Guan-Nan; Liu, Feng-Zhen; Zhang, Bin
作者单位	1.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Gansu, Peoples R China 2.Liaocheng Univ, Liaocheng Peoples Hosp, Med Coll, Liaocheng 252000, Peoples R China 3.Dongchangfu Liaocheng Peoples Hosp, Liaocheng 252000, Peoples R China
推荐引用方式 GB/T 7714	Lv, Zhao-Yong,Chen, Xi-Meng,Zhang, Yu-Jue,et al. Critical-Size Defects of Animal Models for Bone Regeneration[J]. JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING,2018,8(6):761-770.
APA	Lv, Zhao-Yong.,Chen, Xi-Meng.,Zhang, Yu-Jue.,Li, June.,Zhao, Zhong-Hui.,...&Zhang, Bin.(2018).Critical-Size Defects of Animal Models for Bone Regeneration.JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING,8(6),761-770.
MLA	Lv, Zhao-Yong,et al."Critical-Size Defects of Animal Models for Bone Regeneration".JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING 8.6(2018):761-770.