Anaerobic biodegradation of trimethoprim with sulfate as an electron acceptor

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 中国科学院环境生物技术重点实验室

	Anaerobic biodegradation of trimethoprim with sulfate as an electron acceptor
	Liang, Bin ; Kong, Deyong ; Qi, Mengyuan ; Yun, Hui ; Li, Zhiling ; Shi, Ke ; Chen, E.; Vangnai, Alisa S.; Wang, Aijie
刊名	FRONTIERS OF ENVIRONMENTAL SCIENCE & ENGINEERING
	2019-12-01
卷号	13 期号:6 页码:-
关键词	Trimethoprim (TMP) biodegradation Demethylation Sulfate reduction Core microbiome Antibiotic fate
ISSN号	2095-2201
英文摘要	Trimethoprim (TMP) is an antibiotic frequently detected in various environments. Microorganisms are the main drivers of emerging antibiotic contaminant degradation in the environment. However, the feasibility and stability of the anaerobic biodegradation of TMP with sulfate as an electron acceptor remain poorly understood. Here, TMP-degrading microbial consortia were successfully enriched from municipal activated sludge (AS) and river sediment (RS) as the initial inoculums. The acclimated consortia were capable of transforming TMP through demethylation, and the hydroxyl-substituted demethylated product (4-desmethyl-TMP) was further degraded. The biodegradation of TMP followed a 3-parameter sigmoid kinetic model. The potential degraders (Acetobacterium, Desulfovibrio, Desulfobulbus, and unidentified Peptococcaceae) and fermenters (Lentimicrobium and Petrimonas) were significantly enriched in the acclimated consortia. The AS- and RS-acclimated TMP-degrading consortia had similar core microbiomes. The anaerobic biodegradation of TMP could be coupled with sulfate respiration, which gives new insights into the antibiotic fate in real environments and provides a new route for the bioremediation of antibiotic-contaminated environments. (c) Higher Education Press and Springer-Verlag GmbH Germany, part of Springer Nature 2019
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/43331]
专题	生态环境研究中心_中国科学院环境生物技术重点实验室
作者单位	1.Shenyang Acad Environm Sci, Shenyang 110167, Liaoning, Peoples R China 2.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, Key Lab Environm Biotechnol, Beijing 100085, Peoples R China 3.Harbin Inst Technol, Sch Environm, State Key Lab Urban Water Resource & Environm, Harbin 150090, Heilongjiang, Peoples R China
推荐引用方式 GB/T 7714	Liang, Bin,Kong, Deyong,Qi, Mengyuan,et al. Anaerobic biodegradation of trimethoprim with sulfate as an electron acceptor[J]. FRONTIERS OF ENVIRONMENTAL SCIENCE & ENGINEERING,2019,13(6):-.
APA	Liang, Bin.,Kong, Deyong.,Qi, Mengyuan.,Yun, Hui.,Li, Zhiling.,...&Wang, Aijie.(2019).Anaerobic biodegradation of trimethoprim with sulfate as an electron acceptor.FRONTIERS OF ENVIRONMENTAL SCIENCE & ENGINEERING,13(6),-.
MLA	Liang, Bin,et al."Anaerobic biodegradation of trimethoprim with sulfate as an electron acceptor".FRONTIERS OF ENVIRONMENTAL SCIENCE & ENGINEERING 13.6(2019):-.