High-resolution mass spectrometry (HRMS) methods for nontarget discovery and characterization of poly- and per-fluoroalkyl substances (PFASs) in environmental and human samples

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 环境化学与生态毒理学国家重点实验室

	High-resolution mass spectrometry (HRMS) methods for nontarget discovery and characterization of poly- and per-fluoroalkyl substances (PFASs) in environmental and human samples
	Liu, Yanna 4; D'Agostino, Lisa A.; Qu, Guangbo 2,5; Jiang, Guibin 2,5; Martin, Jonathan W.
刊名	TRAC-TRENDS IN ANALYTICAL CHEMISTRY
	2019-12-01
卷号	121 页码:-
关键词	High-resolution mass spectrometry (HRMS) Poly-/per-fluoroalkyl substances (PFASs) Nontarget discovery PFAS-Feature identification Suspect screening
ISSN号	0165-9936
英文摘要	Widespread environmental contamination of legacy long-chain poly- and per-fluoroalkyl substances (PFASs) has triggered chemical regulatory action and a global transitioning to alternative PFASs. More than 5000 PFASs are now recognized on various lists, but few have been monitored despite ample evidence of unidentified organic fluorine in human and environmental samples. Nevertheless, our review of the literature indicates that nontarget analytical methods based on high-resolution mass spectrometry have been used to discover more than 750 PFASs, belonging to more than 130 diverse classes, in strategically selected environmental samples, biofluids or commercial products. Among these reports, we summarize the analytical and data-processing strategies for nontarget PFAS discovery, identify knowledge gaps and propose new areas for method development. Discovery of emerging PFASs before they are global contaminants could mitigate future contamination if strategic techniques can be developed to prioritize some of these substances for synthesis and confirmation, further monitoring, source elucidation and hazard characterization. (c) 2019 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/42548]
专题	生态环境研究中心_环境化学与生态毒理学国家重点实验室
作者单位	1.Jianghan Univ, Inst Environm & Hlth, Wuhan 430056, Hubei, Peoples R China 2.D'Agostino, Lisa A.; Martin, Jonathan W.] Stockholm Univ, Dept Environm Sci & Analyt Chem, Sci Life Lab, S-10691 Stockholm, Sweden 3.Univ Alberta, Dept Lab Med & Pathol, Div Analyt & Environm Tox, Edmonton, AB T6G 2G3, Canada 4.Chinese Acad Sci, Ecoenvironm Sci Res Ctr, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China 5.Univ Chinese Acad Sci, Coll Resources & Environm, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Liu, Yanna,D'Agostino, Lisa A.,Qu, Guangbo,et al. High-resolution mass spectrometry (HRMS) methods for nontarget discovery and characterization of poly- and per-fluoroalkyl substances (PFASs) in environmental and human samples[J]. TRAC-TRENDS IN ANALYTICAL CHEMISTRY,2019,121:-.
APA	Liu, Yanna,D'Agostino, Lisa A.,Qu, Guangbo,Jiang, Guibin,&Martin, Jonathan W..(2019).High-resolution mass spectrometry (HRMS) methods for nontarget discovery and characterization of poly- and per-fluoroalkyl substances (PFASs) in environmental and human samples.TRAC-TRENDS IN ANALYTICAL CHEMISTRY,121,-.
MLA	Liu, Yanna,et al."High-resolution mass spectrometry (HRMS) methods for nontarget discovery and characterization of poly- and per-fluoroalkyl substances (PFASs) in environmental and human samples".TRAC-TRENDS IN ANALYTICAL CHEMISTRY 121(2019):-.