Exploring the bactericidal performance and application of novel mimic enzyme Co4S3

doi:10.1016/j.jcis.2019.10.110

CORC > 海洋研究所 > 中国科学院海洋研究所 > 海洋腐蚀与防护研究发展中心

	Exploring the bactericidal performance and application of novel mimic enzyme Co4S3
	Wang, Jin 1,2,3,4; Wang, Yi 2,3,4; Zhang, Dun 2,3,4
刊名	JOURNAL OF COLLOID AND INTERFACE SCIENCE
	2020-03-01
卷号	561 页码:327-337
关键词	Co4S3 Enzyme mimic Sterilization Hydrogen peroxide L-cysteine Colorimetric detection
ISSN号	0021-9797
DOI	10.1016/j.jcis.2019.10.110
通讯作者	Wang, Yi(wangyi@qdio.ac.cn) ; Zhang, Dun(zhangdun@qdio.ac.cn)
英文摘要	Novel and uniform Co4S3 nanoparticles were synthesized through a two-step hydrothermal process and testified to possess intrinsic peroxidase (POx)-like activity for the first time. As a fresh POx mimic, we studied its catalytic properties, kinetic, and mechanism to catalyze the oxidation of 3, 3', 5, 5'-tetramethylbenzidine in the presence of H2O2. According to the experiments, the bactericidal mechanism is the same as that of simulated enzyme. Based on the ability of Co4S3 inducing H2O2 to express center dot O-2(-), the bactericidal rate can be as high as 100%. Besides, using the POx-like activity of Co4S3, a new off-on sensor for H2O2 and L-cysteine (L-Cys) detection is constructed. The sensor reveals a good wide linear response to H2O2 in the 40-2000 mu M with a detection limit of 18 mu M, while L-Cys in the 20-100 mu M with a detection limit of 10 mM. The proposed method also shows great stability, high selectivity, and excellent practicability. (C) 2019 Elsevier Inc. All rights reserved.
资助项目	National Key Research and Development Program of China[2016YFC1400605] ; Natured Science Foundation of China[41776090] ; Key Research and Development Program of Shandong Province[2018GHY115038] ; AoShan Talent Program ; Qingdao National Laboratory for Marine Science and Technology
WOS研究方向	Chemistry
语种	英语
出版者	ACADEMIC PRESS INC ELSEVIER SCIENCE
WOS记录号	WOS:000508752600031
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/164433]
专题	海洋研究所_海洋腐蚀与防护研究发展中心
通讯作者	Wang, Yi; Zhang, Dun
作者单位	1.Univ Chinese Acad Sci, 19 Jia Yuquan Rd, Beijing 100039, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Environm Corros & Biofouling, Qingdao 266071, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Open Studio Marine Corros & Protect, 1 Wenhai Rd, Qingdao 266237, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Megasci, 7 Nanhai Rd, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Wang, Jin,Wang, Yi,Zhang, Dun. Exploring the bactericidal performance and application of novel mimic enzyme Co4S3[J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE,2020,561:327-337.
APA	Wang, Jin,Wang, Yi,&Zhang, Dun.(2020).Exploring the bactericidal performance and application of novel mimic enzyme Co4S3.JOURNAL OF COLLOID AND INTERFACE SCIENCE,561,327-337.
MLA	Wang, Jin,et al."Exploring the bactericidal performance and application of novel mimic enzyme Co4S3".JOURNAL OF COLLOID AND INTERFACE SCIENCE 561(2020):327-337.