Dietary Different Replacement Levels of Fishmeal by Fish Silage Could Influence Growth of Litopenaeus vannamei by Regulating mTOR at Transcriptional Level

doi:10.3389/fphys.2020.00359

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	Dietary Different Replacement Levels of Fishmeal by Fish Silage Could Influence Growth of Litopenaeus vannamei by Regulating mTOR at Transcriptional Level
	Shao, Jianchun 1,4; Wang, Lei 3,4; Shao, Xuqing 2; Liu, Mei 3,4
刊名	FRONTIERS IN PHYSIOLOGY
	2020-05-06
卷号	11 页码:9
关键词	Litopenaeus vannamei fish silage growth performance intestinal histopathology mammalian target of rapamycin signaling pathway
ISSN号	1664-042X
DOI	10.3389/fphys.2020.00359
通讯作者	Shao, Jianchun(shaojianchun16@mails.ucas.ac.cn) ; Liu, Mei(liumei@qdio.ac.cn)
英文摘要	Fish silage (FS) has been confirmed as a high-quality feed ingredient because of its balanced nutrition, low cost, and environmental friendliness. In the present study, we evaluated the performance of replacing fishmeal by FS in the diet of white shrimp, Litopenaeus vannamei. Five isonitrogenous (410 g kg(-1)) and isolipidic (75 g kg(-1)) diets were formulated with replacement of fishmeal by 0% (FM), 25% (FS25%), 50% (FS50%), 75% (FS75%), and 100% (FS100%) FS. After an 8-week trial, shrimps fed low FS diets (FM and FS25%) had significantly higher final weight (FW), weight gain (WG), and specific growth ratio (SGR) (P < 0.05). No significant differences were found in body composition and most antioxidant enzyme activities of all groups (P > 0.05). Compared to high FS groups (FS75% and FS100%), low FS replacement levels (0 and 25%) had enhanced trypsin activity. And trypsin transcriptional level presented a similar trend with trypsin activity. In terms of intestinal histopathology, no obvious histological damage was observed in the intestine of all groups. tor and s6k of low replacement level groups (FM and FS25%) were significantly upregulated (P < 0.05), which indicated activation of mammalian target of rapamycin (mTOR) signaling pathway in low FS groups at transcriptional level. The enhanced performances of growth and mTOR signaling pathway in low FS groups (FM and FS25%) provided us some insights into the regulation mechanism of nutrient signal on growth. Based on the above, dietary FS could influence the growth of shrimp by regulating mTOR at the transcriptional level, and FS is a potential substitute of fishmeal in shrimp feed.
资助项目	China Agriculture Research System[CARS-47] ; National Natural Science Foundation of China[41406151] ; Marine S&T Fund of Shandong Province for Pilot National Laboratory for Marine Science and Technology (Qingdao)[2018SDKJ0502-2]
WOS研究方向	Physiology
语种	英语
出版者	FRONTIERS MEDIA SA
WOS记录号	WOS:000536700300001
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/167626]
专题	海洋研究所_实验海洋生物学重点实验室
通讯作者	Shao, Jianchun; Liu, Mei
作者单位	1.Fujian Agr & Forestry Univ, Inst Oceanol, Key Lab Marine Biotechnol Fujian Prov, Fuzhou, Peoples R China 2.Shandong Cigna Detect Technol Co Ltd, Qingdao, Peoples R China 3.Chinese Acad Sci, CAS Key Lab Expt Marine Biol, Inst Oceanol, Qingdao, Peoples R China 4.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Peoples R China
推荐引用方式 GB/T 7714	Shao, Jianchun,Wang, Lei,Shao, Xuqing,et al. Dietary Different Replacement Levels of Fishmeal by Fish Silage Could Influence Growth of Litopenaeus vannamei by Regulating mTOR at Transcriptional Level[J]. FRONTIERS IN PHYSIOLOGY,2020,11:9.
APA	Shao, Jianchun,Wang, Lei,Shao, Xuqing,&Liu, Mei.(2020).Dietary Different Replacement Levels of Fishmeal by Fish Silage Could Influence Growth of Litopenaeus vannamei by Regulating mTOR at Transcriptional Level.FRONTIERS IN PHYSIOLOGY,11,9.
MLA	Shao, Jianchun,et al."Dietary Different Replacement Levels of Fishmeal by Fish Silage Could Influence Growth of Litopenaeus vannamei by Regulating mTOR at Transcriptional Level".FRONTIERS IN PHYSIOLOGY 11(2020):9.