Antimicrobial bisabolane-type sesquiterpenoids from the deep-sea sediment-derived fungus Aspergillus versicolor SD-330

doi:10.1080/14786419.2019.1696792

CORC > 海洋研究所 > 中国科学院海洋研究所 > 实验海洋生物学重点实验室

	Antimicrobial bisabolane-type sesquiterpenoids from the deep-sea sediment-derived fungus Aspergillus versicolor SD-330
	Li, Xiao-Dong 1,2; Li, Xin 1,3,4; Li, Xiao-Ming 1,3,4; Yin, Xiu-Li 2; Wang, Bin-Gui 1,3,4
刊名	NATURAL PRODUCT RESEARCH
	2019-11-28
页码	7
关键词	Aspergillus versicolor deep-sea sediment-derived fungus bisabolene-type sesquiterpenoids antimicrobial activity
ISSN号	1478-6419
DOI	10.1080/14786419.2019.1696792
通讯作者	Wang, Bin-Gui(wangbg@ms.qdio.ac.cn)
英文摘要	One new aromatic bisabolene-type sesquiterpenoid (1), along with four known analogues (2-5) were isolated and identified from the deep-sea sediment-derived fungus Aspergillus versicolor SD-330. Their structures were elucidated by NMR, HRESIMS, X-ray crystallographic analysis, and quantum chemical ECD calculations as well as comparison of those data with literature data. Compounds 1-5 were evaluated for antimicrobial activities against human and aquatic pathogenic bacteria. Compounds 1, 2 and 5 exhibited selective inhibitory activities against zoonotic pathogenic bacteria such as Aeromonas hydrophilia, Escherichia coli, Edwardsiella tarda and Vibrio harveyi, with the MIC values ranging from 1.0 to 8.0 mu g/mL.
资助项目	Aoshan Scientific and Technological Innovation Project of Qingdao National Laboratory for Marine Science and Technology[2016ASKJ14] ; National Natural Science Foundation of China[31700043] ; National Natural Science Foundation of China[81600672] ; Key Research and Development Program of Shandong Province[2019GSF107091] ; China Postdoctoral Science Foundation[2016LH00033] ; China Postdoctoral Science Foundation[2017M612358] ; China Postdoctoral Science Foundation[2017M612360] ; Research Vessel KEXUE of the National Major Science and Technology Infrastructure from the Chinese Academy of Sciences[KEXUE2018G28] ; Taishan Scholar Project from Shandong Province ; Shandong Provincial Natural Science Foundation[ZR2017BB073]
WOS研究方向	Chemistry ; Pharmacology & Pharmacy
语种	英语
出版者	TAYLOR & FRANCIS LTD
WOS记录号	WOS:000501477400001
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/163819]
专题	海洋研究所_实验海洋生物学重点实验室
通讯作者	Wang, Bin-Gui
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao, Shandong, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Shandong, Peoples R China 3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Li, Xiao-Dong,Li, Xin,Li, Xiao-Ming,et al. Antimicrobial bisabolane-type sesquiterpenoids from the deep-sea sediment-derived fungus Aspergillus versicolor SD-330[J]. NATURAL PRODUCT RESEARCH,2019:7.
APA	Li, Xiao-Dong,Li, Xin,Li, Xiao-Ming,Yin, Xiu-Li,&Wang, Bin-Gui.(2019).Antimicrobial bisabolane-type sesquiterpenoids from the deep-sea sediment-derived fungus Aspergillus versicolor SD-330.NATURAL PRODUCT RESEARCH,7.
MLA	Li, Xiao-Dong,et al."Antimicrobial bisabolane-type sesquiterpenoids from the deep-sea sediment-derived fungus Aspergillus versicolor SD-330".NATURAL PRODUCT RESEARCH (2019):7.