Quantizing single-molecule surface-enhanced Raman scattering with DNA origami metamolecules

doi:10.1126/sciadv.aau4506

CORC > 上海应用物理研究所 > 中国科学院上海应用物理研究所 > 中科院上海应用物理研究所2011-2017年

	Quantizing single-molecule surface-enhanced Raman scattering with DNA origami metamolecules
	Fang, WN ; Jia, SS ; Chao, J ; Wang, LQ ; Duan, XY ; Liu, HJ ; Li, Q ; Zuo, XL ; Wang, LH ; Wang, LH
刊名	SCIENCE ADVANCES
	2019
卷号	5 期号:9 页码:-
关键词	NANOPARTICLES NANOANTENNAS DIMERS LIGHT
ISSN号	2375-2548
DOI	10.1126/sciadv.aau4506
文献子类	期刊论文
英文摘要	Tailored metal nanoclusters have been actively developed to manipulate light at the subwavelength scale for nanophotonic applications. Nevertheless, precise arrangement of molecules in a hot spot with fixed numbers and positions remains challenging. Here, we show that DNA origami metamolecules with Fano resonances (DMFR) can precisely localize single dye molecules and produce quantified surface-enhanced Raman scattering (SERS) responses. To enable tailored plasmonic permutations, we develop a general and programmable method for anchoring a set of large gold nanoparticles (L-AuNPs) on prescribed n-tuple docking sites of super-origami DNA frameworks. A tetrameric nanocluster with four spatially organized 80-nm L-AuNPs exhibits peak-and-dip Fano characteristics. The drastic enhancement at the wavelength of the Fano minimum allows the collection of prominent SERS spectrum for even a single dye molecule. We expect that DMFR provides physical insights into single-molecule SERS and opens new opportunities for developing plasmonic nanodevices for ultrasensitive sensing, nanocircuits, and nanophotonic lasers.
语种	英语
内容类型	期刊论文
源URL	[http://ir.sinap.ac.cn/handle/331007/32175]
专题	上海应用物理研究所_中科院上海应用物理研究所2011-2017年
作者单位	1.East China Normal Univ, Sch Chem & Mol Engn, Shanghai Key Lab Green Chem & Chem Proc, 500 Dongchuan Rd, Shanghai 200241, Peoples R China 2.Shanghai Jiao Tong Univ, Sch Med, Renji Hosp, Sch Chem & Chem Engn, Shanghai 200240, Peoples R China; 3.Shanghai Jiao Tong Univ, Sch Med, Renji Hosp, Inst Mol Med, Shanghai 200240, Peoples R China; 4.Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai Synchrotron Radiat Facil, CAS Key Lab Interfacial Phys & Technol, Shanghai 201800, Peoples R China; 5.Nanjing Univ Posts & Telecommun, IAM, KLOEID, 9 Wenyuan Rd, Nanjing 210046, Jiangsu, Peoples R China; 6.Nanjing Univ Posts & Telecommun, Sch Mat Sci & Engn, 9 Wenyuan Rd, Nanjing 210046, Jiangsu, Peoples R China; 7.Max Planck Inst Intelligent Syst, Heisenbergstr 3, D-70569 Stuttgart, Germany; 8.Heidelberg Univ, Kirchhoff Inst Phys, Neuenheimer Feld 227, D-69120 Heidelberg, Germany; 9.Tongji Univ, Sch Chem Sci & Engn, Shanghai 200092, Peoples R China;
推荐引用方式 GB/T 7714	Fang, WN,Jia, SS,Chao, J,et al. Quantizing single-molecule surface-enhanced Raman scattering with DNA origami metamolecules[J]. SCIENCE ADVANCES,2019,5(9):-.
APA	Fang, WN.,Jia, SS.,Chao, J.,Wang, LQ.,Duan, XY.,...&Fan, CH.(2019).Quantizing single-molecule surface-enhanced Raman scattering with DNA origami metamolecules.SCIENCE ADVANCES,5(9),-.
MLA	Fang, WN,et al."Quantizing single-molecule surface-enhanced Raman scattering with DNA origami metamolecules".SCIENCE ADVANCES 5.9(2019):-.