Conscious Awareness Differentially Shapes Analgesic and Hyperalgesic Pain Responses

doi:10.1037/xge0000759

CORC > 心理研究所 > 中国科学院心理研究所 > 中国科学院心理健康重点实验室

	Conscious Awareness Differentially Shapes Analgesic and Hyperalgesic Pain Responses
	Liu, Cuizhen 5; Pu, Min 1,4; Lian, Weicheng 1,4; Hu, Li 3; Mobbs, Dean 2; Yu, Rongjun 5
刊名	JOURNAL OF EXPERIMENTAL PSYCHOLOGY-GENERAL
	2020-11-01
卷号	149 期号:11 页码:2007-2019
关键词	conditioning awareness analgesic placebo hyperalgesic nocebo
ISSN号	0096-3445
DOI	10.1037/xge0000759
通讯作者	Yu, Rongjun(psyyr@nus.edu.sg)
英文摘要	A large proportion of human cognitive processes may operate outside of conscious awareness. Subliminally presented visual stimuli that are not consciously perceived have a pervasive effect on behavioral and autonomic responses. Recent studies have claimed that placebo/nocebo effects, which are previously thought to require conscious expectancies, can be elicited to comparable levels regardless of whether the stimuli were consciously perceived or not. We systematically explored the role of consciousness in conditioned analgesic and hyperalgesic pain responses using both classical delay conditioning procedure and trace conditioning procedure. In 2 experiments (total N = 247), we found that analgesic and hyperalgesic responses were differentially dependent on the conscious awareness of the relevant stimuli. Specifically, the analgesic response was only significant when stimuli were supraliminal in both conditioning/acquisition phase and test/activation phases. While the hyperalgesic responses were acquired and activated irrespective of stimulus exposure (supraliminal/subliminal), the magnitude of this response was larger when stimuli were supraliminal in the test stage. Our results indicate that analgesic responses require both conscious conditioning and conscious activation, challenging the view that classical conditioning of analgesic pain responses operates without conscious awareness. Hyperalgesic responses are generally not dependent on the consciousness of stimuli, suggesting the presence of a valence-specific rapid regulatory mechanism to enable adaptive responses in threatening circumstances. Our study demonstrates a nascent role of consciousness in the learning of complex cognitive processes.
WOS关键词	NONCONSCIOUS ACTIVATION ; PLACEBO ANALGESIA ; HUMAN DELAY ; NOCEBO ; FEAR ; TRACE ; EXPECTATIONS ; EXPECTANCY ; MECHANISMS ; EXPERIENCE
WOS研究方向	Psychology
语种	英语
出版者	AMER PSYCHOLOGICAL ASSOC
WOS记录号	WOS:000585909700001
内容类型	期刊论文
源URL	[http://ir.psych.ac.cn/handle/311026/38458]
专题	心理研究所_中国科学院心理健康重点实验室
通讯作者	Yu, Rongjun
作者单位	1.South China Normal Univ, Ctr Studies Psychol Applicat, Guangzhou, Peoples R China 2.CALTECH, Div Humil & Social Sci, Computat & Neural Syst Program, Pasadena, CA 91125 USA 3.Chinese Acad Sci, Inst Psychol, Lab Mental Hlth, Beijing, Peoples R China 4.South China Normal Univ, Sch Psychol, Guangzhou, Peoples R China 5.Natl Univ Singapore, Dept Psychol, 9 Arts Link, Singapore 117570, Singapore
推荐引用方式 GB/T 7714	Liu, Cuizhen,Pu, Min,Lian, Weicheng,et al. Conscious Awareness Differentially Shapes Analgesic and Hyperalgesic Pain Responses[J]. JOURNAL OF EXPERIMENTAL PSYCHOLOGY-GENERAL,2020,149(11):2007-2019.
APA	Liu, Cuizhen,Pu, Min,Lian, Weicheng,Hu, Li,Mobbs, Dean,&Yu, Rongjun.(2020).Conscious Awareness Differentially Shapes Analgesic and Hyperalgesic Pain Responses.JOURNAL OF EXPERIMENTAL PSYCHOLOGY-GENERAL,149(11),2007-2019.
MLA	Liu, Cuizhen,et al."Conscious Awareness Differentially Shapes Analgesic and Hyperalgesic Pain Responses".JOURNAL OF EXPERIMENTAL PSYCHOLOGY-GENERAL 149.11(2020):2007-2019.