Brain-wide resting-state connectivity regulation by the hippocampus and medial prefrontal cortex is associated with fluid intelligence | |
Li, Rui3,4; Zhang, Jing2; Wu, Xia1; Wen, Xiaotong2; Han, Buxin3,4 | |
刊名 | BRAIN STRUCTURE & FUNCTION |
2020-04-24 | |
页码 | 14 |
关键词 | Connectivity Hippocampus Intelligence Medial prefrontal Resting state |
ISSN号 | 1863-2653 |
DOI | 10.1007/s00429-020-02077-8 |
产权排序 | 1 |
文献子类 | SCI |
英文摘要 | The connectivity hub property of the hippocampus (HIP) and the medial prefrontal cortex (MPFC) is essential for their widespread involvement in cognition; however, the cooperation mechanism between them is far from clear. Herein, using resting-state functional MRI and Gaussian Bayesian network to describe the directed organizing architecture of the HIP-MPFC pathway with regions in the brain, we demonstrated that the HIP and the MPFC have central roles as the driving hub and aggregating hub, respectively. The status of the HIP and the MPFC is dominant in communications between the HIP and the default-mode network, between the HIP and core neurocognitive networks, including the default-mode, frontoparietal, and salience networks, and between brain-wide representative regions, suggesting a strong and robust central position of the two regions in regulating the dynamics of large-scale brain activity. Furthermore, we found that the directed connectivity and flow from the right HIP to the MPFC is significantly linked to fluid intelligence. Together, these results clarify the different roles of the HIP and the MPFC that jointly contribute to network dynamics and cognitive ability from a data-driven insight via the use of the directed connectivity method. |
资助项目 | fund for building world-class universities (disciplines) of Renmin University of China[2018] |
WOS关键词 | INDEPENDENT COMPONENT ANALYSIS ; FUNCTIONAL CONNECTIVITY ; DEFAULT MODE ; NEURAL MECHANISMS ; NETWORK ; MEMORY ; ORGANIZATION ; MRI ; REGISTRATION ; OSCILLATIONS |
WOS研究方向 | Anatomy & Morphology ; Neurosciences & Neurology |
语种 | 英语 |
出版者 | SPRINGER HEIDELBERG |
WOS记录号 | WOS:000528517800001 |
资助机构 | fund for building world-class universities (disciplines) of Renmin University of China |
内容类型 | 期刊论文 |
源URL | [http://ir.psych.ac.cn/handle/311026/31704] |
专题 | 心理研究所_中国科学院心理健康重点实验室 |
通讯作者 | Li, Rui |
作者单位 | 1.Beijing Normal Univ, Coll Informat Sci & Technol, Beijing, Peoples R China 2.Renmin Univ China, Dept Psychol, Beijing, Peoples R China 3.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 4.Inst Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China |
推荐引用方式 GB/T 7714 | Li, Rui,Zhang, Jing,Wu, Xia,et al. Brain-wide resting-state connectivity regulation by the hippocampus and medial prefrontal cortex is associated with fluid intelligence[J]. BRAIN STRUCTURE & FUNCTION,2020:14. |
APA | Li, Rui,Zhang, Jing,Wu, Xia,Wen, Xiaotong,&Han, Buxin.(2020).Brain-wide resting-state connectivity regulation by the hippocampus and medial prefrontal cortex is associated with fluid intelligence.BRAIN STRUCTURE & FUNCTION,14. |
MLA | Li, Rui,et al."Brain-wide resting-state connectivity regulation by the hippocampus and medial prefrontal cortex is associated with fluid intelligence".BRAIN STRUCTURE & FUNCTION (2020):14. |
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