An efficient strategy for circulating tumor cell detection: surface-enhanced Raman spectroscopy

doi:10.1039/c9tb02327e

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	An efficient strategy for circulating tumor cell detection: surface-enhanced Raman spectroscopy
	Lin, Jie ; Zheng, Jianping ; Wu, Aiguo
刊名	JOURNAL OF MATERIALS CHEMISTRY B
	2020
卷号	8 期号:16 页码:3316-3326
关键词	MOLECULAR-DETECTION SCATTERING TAGS QUANTUM DOTS GRAPHENE NANOPARTICLES CAPTURE SILVER EXPRESSION SUBSTRATE AG
DOI	10.1039/c9tb02327e
英文摘要	Circulating tumor cells (CTCs) are circulating cancer cells that shed from tumor tissue into blood vessels and circulate in the blood to invade other organs, which results in fatal metastases. The CTCs in human peripheral blood are the main cause of death in most cancer patients. The detection of CTCs is of great scientific significance and clinical application value for early diagnosis, rapid evaluation of the treatment effect, in vivo drug resistance testing, individualized treatment, tumor recurrence detection and survival time judgment, etc. The surface-enhanced Raman scattering (SERS) method possesses the features of remarkable detection sensitivity, a non-destructive nature, label-free detection, a quick spectrum response and a molecular fingerprint spectrum, which give it great potential in the detection field. In the past decade, SERS technology serving as a bioprobe has been increasingly applied to detect and analyze biological components due to its unique detection advantages. Here, we present an overview of SERS biosensing substrates and recent achievements in detecting CTCs using high-sensitivity SERS platforms, and provide a unique perspective on the design and application of high-performance SERS platforms for CTC detection, especially using non-metal materials.
学科主题	Materials Science
内容类型	期刊论文
源URL	[http://ir.nimte.ac.cn/handle/174433/19755]
专题	2020专题
作者单位	1.Zheng, JP 2.Wu, AG (corresponding author), Chinese Acad Sci, Ningbo Inst Mat Technol & Engn, Key Lab Magnet Mat & Devices, Cixi Inst Biomed Engn, 1219 ZhongGuan West Rd, Ningbo 315201, Peoples R China.
推荐引用方式 GB/T 7714	Lin, Jie,Zheng, Jianping,Wu, Aiguo. An efficient strategy for circulating tumor cell detection: surface-enhanced Raman spectroscopy[J]. JOURNAL OF MATERIALS CHEMISTRY B,2020,8(16):3316-3326.
APA	Lin, Jie,Zheng, Jianping,&Wu, Aiguo.(2020).An efficient strategy for circulating tumor cell detection: surface-enhanced Raman spectroscopy.JOURNAL OF MATERIALS CHEMISTRY B,8(16),3316-3326.
MLA	Lin, Jie,et al."An efficient strategy for circulating tumor cell detection: surface-enhanced Raman spectroscopy".JOURNAL OF MATERIALS CHEMISTRY B 8.16(2020):3316-3326.