Super-resolution nanoscopy by coherent control on nanoparticle emission

doi:10.1126/sciadv.aaw6579

CORC > 计算技术研究所 > 中国科学院计算技术研究所 > 中国科学院计算技术研究所期刊论文 > 英文

	Super-resolution nanoscopy by coherent control on nanoparticle emission
	Liu, Congyue 1; Liu, Wei 1; Wang, Shufeng 1,2,3; Li, Hongjia 4,5; Lv, Zhilong 4,5; Zhang, Fa 4; Zhang, Donghui 6,7; Teng, Junlin 6,7; Zheng, Tao 8; Li, Donghai 9
刊名	SCIENCE ADVANCES
	2020-04-01
卷号	6 期号:16 页码:8
ISSN号	2375-2548
DOI	10.1126/sciadv.aaw6579
英文摘要	Super-resolution nanoscopy based on wide-field microscopic imaging provided high efficiency but limited resolution. Here, we demonstrate a general strategy to push its resolution down to -50 nm, which is close to the range of single molecular localization microscopy, without sacrificing the wide-field imaging advantage. It is done by actively and simultaneously modulating the characteristic emission of each individual emitter at high density. This method is based on the principle of excited state coherent control on single-particle two-photon fluorescence. In addition, the modulation efficiently suppresses the noise for imaging. The capability of the method is verified both in simulation and in experiments on ZnCdS quantum dot-labeled films and COS7 cells. The principle of coherent control is generally applicable to single-multiphoton imaging and various probes.
资助项目	National Key Research and Development Program[2016YFB0401003] ; National Key Research and Development Program[2017YFA0504702] ; National Natural Science Foundation of China[91750203] ; National Natural Science Foundation of China[11527901] ; National Natural Science Foundation of China[11874074] ; National Natural Science Foundation of China[61775004] ; National Natural Science Foundation of China[61575005] ; National Natural Science Foundation of China[11574009] ; National Natural Science Foundation of China[31421002] ; National Natural Science Foundation of China[U1611261] ; National Natural Science Foundation of China[U1611263] ; National Natural Science Foundation of China[U1605244]
WOS研究方向	Science & Technology - Other Topics
语种	英语
出版者	AMER ASSOC ADVANCEMENT SCIENCE
WOS记录号	WOS:000528276800002
内容类型	期刊论文
源URL	[http://119.78.100.204/handle/2XEOYT63/15451]
专题	中国科学院计算技术研究所期刊论文_英文
通讯作者	Wang, Shufeng; Zhang, Fa; Gong, Qihuang
作者单位	1.Peking Univ, Dept Phys, State Key Lab Artificial Microstruct & Mesoscop P, Beijing 100871, Peoples R China 2.Shanxi Univ, Collaborat Innovat Ctr Extreme Opt, Taiyuan 030006, Peoples R China 3.Peking Univ, Frontiers Sci Ctr Nanooptoelect, Collaborat Innovat Ctr Quantum Matter, Beijing 100871, Peoples R China 4.Chinese Acad Sci, High Performance Comp Res Ctr, Inst Comp Technol, Beijing, Peoples R China 5.Univ Chinese Acad Sci, Beijing, Peoples R China 6.Peking Univ, Coll Life Sci, Key Lab Cell Proliferat & Differentiat, Minist Educ, Beijing 100871, Peoples R China 7.Peking Univ, Coll Life Sci, State Key Lab Membrane Biol, Beijing 100871, Peoples R China 8.Peking Univ, Acad Adv Interdisciplinary Studies, Peking Tsinghua Ctr Life Sci, Beijing 100871, Peoples R China 9.Univ Wurzburg, Inst Phys & Theoret Chem, D-97074 Wurzburg, Germany 10.Chinese Acad Sci, Inst Biophys, Key Lab RNA Biol, Beijing 100101, Peoples R China
推荐引用方式 GB/T 7714	Liu, Congyue,Liu, Wei,Wang, Shufeng,et al. Super-resolution nanoscopy by coherent control on nanoparticle emission[J]. SCIENCE ADVANCES,2020,6(16):8.
APA	Liu, Congyue.,Liu, Wei.,Wang, Shufeng.,Li, Hongjia.,Lv, Zhilong.,...&Gong, Qihuang.(2020).Super-resolution nanoscopy by coherent control on nanoparticle emission.SCIENCE ADVANCES,6(16),8.
MLA	Liu, Congyue,et al."Super-resolution nanoscopy by coherent control on nanoparticle emission".SCIENCE ADVANCES 6.16(2020):8.