Evaluation of Trace Element Contamination and Health Risks of Medicinal Herbs Collected from Unpolluted and Polluted Areas in Sichuan Province, China

doi:10.1007/s12011-020-02539-4

CORC > 成都山地灾害与环境研究所 > 中国科学院水利部成都山地灾害与环境研究所

	Evaluation of Trace Element Contamination and Health Risks of Medicinal Herbs Collected from Unpolluted and Polluted Areas in Sichuan Province, China
	Gao, Jianing 2,3; Zhang, Dan 2; Uwiringiyimana, Ernest 2,3; Proshad, Ram 2,3; Ugurlu, Aysenur 1
刊名	BIOLOGICAL TRACE ELEMENT RESEARCH
	2021
页码	DOI: 10.1007/s12011-020-02539-4
关键词	Trace element contamination Medicinal herb Non-carcinogenic risk Cancer risk Multi-medium exposure
ISSN号	0163-4984
DOI	10.1007/s12011-020-02539-4
通讯作者	Zhang, Dan(daniezhang@imde.ac.cn)
产权排序	1
文献子类	Article;Early Access
英文摘要	Trace element contamination in Chinese herbal medicines has been recognized as a potential health concern for consumers. To assess the health risk to the herb-consuming population, nine trace elements (Cu, Cd, Cr, Mo, Ni, Pb, Sr, Zn, and As) were investigated based on their concentrations in three common medicinal plants (Astragalus membranaceus, Codonopsis tangshen, and Paris polyphylla var. chinensis) and soils from unpolluted and polluted areas in the Sichuan Province, China. The results showed that the metal content differed significantly in medicinal plants and soils from unpolluted versus polluted areas. No significant differences in metal accumulation were observed for these CHMs grown in either unpolluted or polluted areas. Evaluation of the health risk index suggested that soil ingestion and medicated diet represented the dominant exposure routes, indicating that trace metal(loids) in local soil might pose potential risks through soil-food chain transfer. Hazard quotient values for AM (1.473) and CT (1.357) were higher than the standard value (HQ > 1), whereas the hazard indices for PC, AM, and CT were 13.18, 14.33, and 14.01 times higher than the safe limit (HI > 1) in the polluted area, indicating non-cancer-related health hazards. Ingestion of soil was responsible for 36.39 to 91.06% of the total cancer risk and medicated diet accounted for 6.35 to 62.71%, compared with inhalation and dermal contact, suggesting carcinogenic health risks in herbs from polluted soils. In this study, Pb showed relatively higher non-carcinogenic risks, while Cr and Ni posed the highest cancer risks. Therefore, we propose more effective measures, which should be considered for Cr, Ni, and Pb remediation in soil to reduce their pollution in the studied areas.
电子版国际标准刊号	1559-0720
资助项目	Project of University of Chinese Academy of Sciences, the People's Republic of China[KFJ-FP-202006]
WOS关键词	HEAVY-METAL POLLUTION ; SOIL ; ACCUMULATION ; CADMIUM ; CONSUMPTION ; IMPACTS ; SYSTEM ; CD ; CU
WOS研究方向	Biochemistry & Molecular Biology ; Endocrinology & Metabolism
语种	英语
出版者	HUMANA PRESS INC
WOS记录号	WOS:000604196100003
资助机构	Project of University of Chinese Academy of Sciences, the People's Republic of China
内容类型	期刊论文
源URL	[http://ir.imde.ac.cn/handle/131551/55147]
专题	中国科学院水利部成都山地灾害与环境研究所
通讯作者	Zhang, Dan
作者单位	1.Hacettepe Univ, Dept Environm Engn, Ankara, Turkey 2.Chinese Acad Sci, Inst Mt Hazards & Environm, Key Lab Mt Surface Proc & Ecol Regulat, 9,Block 4,Renminnanlu Rd, Chengdu 610041, Sichuan, Peoples R China; 3.Univ Chinese Acad Sci, Beijing, Peoples R China;
推荐引用方式 GB/T 7714	Gao, Jianing,Zhang, Dan,Uwiringiyimana, Ernest,et al. Evaluation of Trace Element Contamination and Health Risks of Medicinal Herbs Collected from Unpolluted and Polluted Areas in Sichuan Province, China[J]. BIOLOGICAL TRACE ELEMENT RESEARCH,2021:DOI: 10.1007/s12011-020-02539-4.
APA	Gao, Jianing,Zhang, Dan,Uwiringiyimana, Ernest,Proshad, Ram,&Ugurlu, Aysenur.(2021).Evaluation of Trace Element Contamination and Health Risks of Medicinal Herbs Collected from Unpolluted and Polluted Areas in Sichuan Province, China.BIOLOGICAL TRACE ELEMENT RESEARCH,DOI: 10.1007/s12011-020-02539-4.
MLA	Gao, Jianing,et al."Evaluation of Trace Element Contamination and Health Risks of Medicinal Herbs Collected from Unpolluted and Polluted Areas in Sichuan Province, China".BIOLOGICAL TRACE ELEMENT RESEARCH (2021):DOI: 10.1007/s12011-020-02539-4.