Green route to synthesize Zinc Oxide Nanoparticles using leaf extracts of Cassia fistula and Melia azadarach and their antibacterial potential

doi:10.1038/s41598-020-65949-3

	Green route to synthesize Zinc Oxide Nanoparticles using leaf extracts of Cassia fistula and Melia azadarach and their antibacterial potential
	Naseer, Minha 6; Aslam, Usman 5; Khalid, Bushra 1,4; Chen, Bin 2,3
刊名	SCIENTIFIC REPORTS
	2020-06-03
卷号	10 期号:1 页码:10
ISSN号	2045-2322
DOI	10.1038/s41598-020-65949-3
通讯作者	Aslam, Usman(usmanaslam@uaf.edu.pk) ; Chen, Bin(chen_bin@mail.iap.ac.cn)
英文摘要	Development of plant based nanoparticles has many advantages over conventional physico-chemical methods and has various applications in medicine and biology. In present study, zinc oxide (ZnO) nanoparticles (NPs) were synthesized using leaf extracts of two medicinal plants Cassia fistula and Melia azadarach. 0.01 M zinc acetate dihydrate was used as a precursor in leaf extracts of respective plants for NPs synthesis. The structural and optical properties of NPs were investigated by X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, scanning electron microscope (SEM), ultraviolet-visible spectrophotometer (UV-Vis) and dynamic light scattering (DLS). The antibacterial potential of ZnO NPs was examined by paper disc diffusion method against two clinical strains of Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) based on the zone of inhibition and minimal inhibitory indices (MIC). Change in color of the reaction mixture from brown to white indicated the formation of ZnO NPs. UV peaks at 320 nm and 324 nm, and XRD pattern matching that of JCPDS card for ZnO confirmed the presence of pure ZnO NPs. FTIR further confirmed the presence of bioactive functional groups involved in the reduction of bulk zinc acetate to ZnO NPs. SEM analysis displayed the shape of NPs to be spherical whereas DLS showed their size range from 3 to 68 nm. The C. fistula and M. azadarach mediated ZnO NPs showed strong antimicrobial activity against clinical pathogens compared to standard drugs, suggesting that plant based synthesis of NPs can be an excellent strategy to develop versatile and eco-friendly biomedical products.
资助项目	International Partnership Program of the Chinese Academy of Sciences[134111KYSB20180021] ; National Natural Science Foundation of China[41590871] ; International Science & Technology Cooperation Program of China[2013DFG22820] ; Department of Microbiology, Pakistan Institute of Medical Sciences (PIMS), Islamabad and Pakistan Institute of Nuclear Science and Technology (PINSTECH), Islamabad, Pakistan
WOS关键词	SILVER NANOPARTICLES ; FABRICATION ; PLANTS
WOS研究方向	Science & Technology - Other Topics
语种	英语
出版者	NATURE PUBLISHING GROUP
WOS记录号	WOS:000543961800031
资助机构	International Partnership Program of the Chinese Academy of Sciences ; National Natural Science Foundation of China ; International Science & Technology Cooperation Program of China ; Department of Microbiology, Pakistan Institute of Medical Sciences (PIMS), Islamabad and Pakistan Institute of Nuclear Science and Technology (PINSTECH), Islamabad, Pakistan
内容类型	期刊论文
源URL	[http://ir.igsnrr.ac.cn/handle/311030/162440]
专题	中国科学院地理科学与资源研究所
通讯作者	Aslam, Usman; Chen, Bin
作者单位	1.Abdus Salam Int Ctr Theoret Phys, Trieste, Italy 2.Nanjing Univ Informat Sci & Technol, Collaborat Innovat Ctr Forecast & Evaluat Meteoro, Nanjing 210044, Peoples R China 3.Chinese Acad Sci, Inst Atmospher Phys, Beijing 100029, Peoples R China 4.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, 11A Datun Rd, Beijing 100101, Peoples R China 5.Univ Agr Faisalabad, Dept Plant Breeding & Genet, Faisalabad, Pakistan 6.Int Islamic Univ Islamabad, Dept Environm Sci, Islamabad, Pakistan
推荐引用方式 GB/T 7714	Naseer, Minha,Aslam, Usman,Khalid, Bushra,et al. Green route to synthesize Zinc Oxide Nanoparticles using leaf extracts of Cassia fistula and Melia azadarach and their antibacterial potential[J]. SCIENTIFIC REPORTS,2020,10(1):10.
APA	Naseer, Minha,Aslam, Usman,Khalid, Bushra,&Chen, Bin.(2020).Green route to synthesize Zinc Oxide Nanoparticles using leaf extracts of Cassia fistula and Melia azadarach and their antibacterial potential.SCIENTIFIC REPORTS,10(1),10.
MLA	Naseer, Minha,et al."Green route to synthesize Zinc Oxide Nanoparticles using leaf extracts of Cassia fistula and Melia azadarach and their antibacterial potential".SCIENTIFIC REPORTS 10.1(2020):10.