Effects of Dietary Supplements on the Bioaccessibility of Se, Zn and Cd in Rice: Preliminary Observations from In Vitro Gastrointestinal Simulation Tests

doi:10.3390/ijerph17144978

	Effects of Dietary Supplements on the Bioaccessibility of Se, Zn and Cd in Rice: Preliminary Observations from In Vitro Gastrointestinal Simulation Tests
	Zhang, Ru 1,2; Li, Yonghua 1; Xu, Yuefeng 1,2; Zang, Zhenfeng 1,2; Li, Hairong 1; Wang, Li 1
刊名	INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
	2020-07-01
卷号	17 期号:14 页码:11
关键词	bioaccessibility dietary supplements gastrointestinal simulation test selenium
DOI	10.3390/ijerph17144978
通讯作者	Li, Yonghua(yhli@igsnrr.ac.cn)
英文摘要	Trace elements such as selenium (Se) and zinc (Zn) are essential elements in the human body, while cadmium (Cd) has no physiological function. A high proportion of people consume dietary supplements to enhance the performance of the body or alter the nutrient contents within the body. Therefore, this study was conducted to evaluate the interaction effects of several popular dietary supplements on the bioaccessibility of Se, Zn and Cd in rice with the hope of identifying dietary supplements that can increase rice Se and Zn bioaccessibility but decrease rice Cd bioaccessibility. The results from in vitro gastrointestinal simulation tests showed that the bioaccessibility of these elements in rice was in the order of Cd (52.07%) > Zn (36.63%) > Se (10.19%) during the gastric phase and Zn (26.82%) > Cd (18.72%) > Se (14.70%) during the intestinal phase. The bioaccessibility of Se during the intestinal phase was greater than that during the gastric phase, and the bioaccessibility of Zn and Cd were the opposite. The bioaccessibility of Se significantly increased in response to vitamin C (VC), vitamin E (VE), vitamin B6 (VB6) and vitamin B9 (VB9), especially VC, which also increased the bioaccessibility of Zn and decreased that of Cd. Procyanidins (OPC), methionine (Met) and coenzyme Q10 (Q10) significantly reduced the bioaccessibility of Se. These results suggest that the reasonable use of dietary supplements can effectively regulate the in vivo contents of trace elements, which provide valuable information for developing health interventions to address problems for specific people, especially selenium-deficient people.
资助项目	Second Tibetan Plateau Scientific Expedition and Research[2019QZKK0607] ; National Natural Science Foundation of China[41671499] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDA19040303]
WOS关键词	OXIDATIVE STRESS ; DIGESTION MODELS ; ASCORBIC-ACID ; HUMAN HEALTH ; SELENIUM ; ZINC ; BIOAVAILABILITY ; CADMIUM ; COOKING ; RISK
WOS研究方向	Environmental Sciences & Ecology ; Public, Environmental & Occupational Health
语种	英语
出版者	MDPI
WOS记录号	WOS:000558026700001
资助机构	Second Tibetan Plateau Scientific Expedition and Research ; National Natural Science Foundation of China ; Strategic Priority Research Program of the Chinese Academy of Sciences
内容类型	期刊论文
源URL	[http://ir.igsnrr.ac.cn/handle/311030/158104]
专题	中国科学院地理科学与资源研究所
通讯作者	Li, Yonghua
作者单位	1.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, Key Lab Land Surface Pattern & Simulat, Beijing 100101, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Ru,Li, Yonghua,Xu, Yuefeng,et al. Effects of Dietary Supplements on the Bioaccessibility of Se, Zn and Cd in Rice: Preliminary Observations from In Vitro Gastrointestinal Simulation Tests[J]. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH,2020,17(14):11.
APA	Zhang, Ru,Li, Yonghua,Xu, Yuefeng,Zang, Zhenfeng,Li, Hairong,&Wang, Li.(2020).Effects of Dietary Supplements on the Bioaccessibility of Se, Zn and Cd in Rice: Preliminary Observations from In Vitro Gastrointestinal Simulation Tests.INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH,17(14),11.
MLA	Zhang, Ru,et al."Effects of Dietary Supplements on the Bioaccessibility of Se, Zn and Cd in Rice: Preliminary Observations from In Vitro Gastrointestinal Simulation Tests".INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 17.14(2020):11.